Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome.
about
Human antibody production in transgenic animalsHigh-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH regionMapping the mouse genome: current status and future prospects.Episomal vectors for gene expression in mammalian cells.Human antibodies from transgenic mice.Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]A method for high efficiency YAC lipofection into murine embryonic stem cellsPassive immunization against dental caries and periodontal disease: development of recombinant and human monoclonal antibodies.Efficient male and female germline transmission of a human chromosomal vector in mice.Advances in monoclonal antibody technology: genetic engineering of mice, cells, and immunoglobulins.YAC transgenes: bigger is probably better.Expression of the human beta-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice.Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic miceHuman artificial episomal chromosomes for cloning large DNA fragments in human cells.Modification of the Genome of Domestic Animals.Antibodies generated from human immunoglobulin miniloci in transgenic mice.A method for the generation of YAC transgenic mice by pronuclear microinjection.Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs.Successful targeting of mouse Y chromosome genes using a site-directed insertion vector.Therapeutic antibodies: magic bullets hit the target.
P2860
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P2860
Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Transgenic mice containing a h ...... a yeast artificial chromosome.
@ast
Transgenic mice containing a h ...... a yeast artificial chromosome.
@en
type
label
Transgenic mice containing a h ...... a yeast artificial chromosome.
@ast
Transgenic mice containing a h ...... a yeast artificial chromosome.
@en
prefLabel
Transgenic mice containing a h ...... a yeast artificial chromosome.
@ast
Transgenic mice containing a h ...... a yeast artificial chromosome.
@en
P2093
P2860
P356
P1433
P1476
Transgenic mice containing a h ...... a yeast artificial chromosome.
@en
P2093
Hollenbach PW
Kurahara CG
Pearson BE
Weddell GN
Woodhouse CS
P2860
P2888
P304
P356
10.1038/NG0693-117
P407
P577
1993-06-01T00:00:00Z