Harnessing CD4⁺ T cell responses in HIV vaccine development.
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CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive VaccinesA Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV ImmunogenIntegrated analysis of residue coevolution and protein structures capture key protein sectors in HIV-1 proteinsHIV-1 vaccines: challenges and new perspectivesInduction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.Immunity to HIV in Early LifeTranscriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional featuresVaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection.Regulation of SIV antigen-specific CD4+ T cellular immunity via autophagosome-mediated MHC II molecule-targeting antigen presentation in mice.Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infectionInterleukin 23 produced by myeloid dendritic cells contributes to T-cell dysfunction in HIV type 1 infection by inducing SOCS1 expressionA Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults.Human immunodeficiency virus vaccinesCodelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques.Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection.NK cells inhibit humoral immunity by reducing the abundance of CD4+ T follicular helper cells during a chronic virus infectionAchieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens.HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell ResponsesNetworking at the level of host immunity: immune cell interactions during persistent viral infectionsCellular and population plasticity of helper CD4(+) T cell responses.Recombinant and epitope-based vaccines on the road to the market and implications for vaccine design and productionExogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1.DNA-MVA-protein vaccination of rhesus macaques induces HIV-specific immunity in mucosal-associated lymph nodes and functional antibodies.Immunogenicity and safety of a booster dose of an investigational adjuvanted polyprotein HIV-1 vaccine in healthy adults and effect of administration of chloroquineAssociation of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune controlHuman circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responsesHIV vaccine research and discovery in the nonhuman primates model: a unified theory in acquisition prevention and control of SIV infectionDynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells.Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination.Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility.HIV vaccines: a brief overview.Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies.C-type lectin receptors in the control of T helper cell differentiation.Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem.CD4 T-Cell Responses in Primary HIV Infection: Interrelationship with Immune Activation and Virus Burden.Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiationHIV Susceptibility of human antigen-specific CD4 T cells in AIDS pathogenesis and vaccine response.T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in mice.Vaccination establishes clonal relatives of germinal center T cells in the blood of humans.
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P2860
Harnessing CD4⁺ T cell responses in HIV vaccine development.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@ast
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@en
type
label
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@ast
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@en
prefLabel
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@ast
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@en
P2093
P2860
P356
P1433
P1476
Harnessing CD4⁺ T cell responses in HIV vaccine development.
@en
P2093
Dan R Littman
M Patricia D'Souza
Shane Crotty
P2860
P2888
P304
P356
10.1038/NM.3054
P407
P577
2013-02-06T00:00:00Z