The cooperative binding of phenylalanine to phenylalanine 4-monooxygenase studied by 1H-NMR paramagnetic relaxation. Changes in water accessibility to the iron at the active site upon substrate binding.
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Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuriaThe accessibility of iron at the active site of recombinant human phenylalanine hydroxylase to water as studied by 1H NMR paramagnetic relaxation. Effect of L-Phe and comparison with the rat enzyme.Allosteric regulation of phenylalanine hydroxylase.Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.Structure and function of the aromatic amino acid hydroxylases.PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain.The effect of substrate, dihydrobiopterin, and dopamine on the EPR spectroscopic properties and the midpoint potential of the catalytic iron in recombinant human phenylalanine hydroxylase.Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis.
P2860
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P2860
The cooperative binding of phenylalanine to phenylalanine 4-monooxygenase studied by 1H-NMR paramagnetic relaxation. Changes in water accessibility to the iron at the active site upon substrate binding.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The cooperative binding of phe ...... e site upon substrate binding.
@ast
The cooperative binding of phe ...... e site upon substrate binding.
@en
type
label
The cooperative binding of phe ...... e site upon substrate binding.
@ast
The cooperative binding of phe ...... e site upon substrate binding.
@en
prefLabel
The cooperative binding of phe ...... e site upon substrate binding.
@ast
The cooperative binding of phe ...... e site upon substrate binding.
@en
P2093
P2860
P1433
P1476
The cooperative binding of phe ...... e site upon substrate binding.
@en
P2093
A Martínez
S Olafsdottir
T Flatmark
P2860
P304
P356
10.1111/J.1432-1033.1993.TB19894.X
P407
P577
1993-01-01T00:00:00Z