Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.
about
Rho GTPases, oxidation, and cell redox controlThe roles of PIKE in tumorigenesisFluctuation of ROS regulates proliferation and mediates inhibition of migration by reducing the interaction between DLC1 and CAV-1 in breast cancer cells.Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivoPiperlongumine inhibits migration of glioblastoma cells via activation of ROS-dependent p38 and JNK signaling pathways.Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins.VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formationGrowth inhibitory effect of Cucurbitacin E on breast cancer cells.Characterization of a P-Rex1 gene signature in breast cancer cellsCucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α.Flavone inhibits migration through DLC1/RhoA pathway by decreasing ROS generation in breast cancer cells.Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture.PKCε Is an Essential Mediator of Prostate Cancer Bone Metastasis.Redox regulation of the actin cytoskeleton and its role in the vascular system.JSI124 inhibits breast cancer cell growth by suppressing the function of B cells via the downregulation of signal transducer and activator of transcription 3.Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary targetIdentification of 16,25--diacetyl-cucurbitane F and 25--acetyl-23,24-dihydrocucurbitacin F as novel anti-cancer chemicals
P2860
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P2860
Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@ast
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@en
type
label
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@ast
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@en
prefLabel
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@ast
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@en
P2860
P356
P1476
Cucurbitacin I inhibits Rac1 a ...... tyrosine kinase 2 and P-Rex1.
@en
P2093
Cynthia Lopez-Haber
Marcelo G Kazanietz
P2860
P304
P356
10.1124/MOL.112.084293
P577
2013-03-11T00:00:00Z