Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans - Wikidata - wikimedia - TriplyDB

Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans

Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans

http://www.wikidata.org/entity/Q36779397

about

Discovery of single-gene inborn errors of immunity by next generation sequencing Protein Kinase C δ: a Gatekeeper of Immune Homeostasis NK Cell Influence on the Outcome of Primary Epstein-Barr Virus Infection Protein kinase C in the immune system: from signalling to chromatin regulation Autoimmunity in primary T-cell immunodeficiencies.Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas.Solving the genetic puzzle of systemic lupus erythematosus.B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia.Protein kinase C δ deficiency enhances megakaryopoiesis and recovery from thrombocytopenia.Advances in the Care of Primary Immunodeficiencies (PIDs): from Birth to Adulthood.CGX1037 is a novel PKC isoform delta selective inhibitor in platelets.Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies.Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor Host genetics of Epstein-Barr virus infection, latency and disease.The expanding spectrum of the autoimmune lymphoproliferative syndromes Utility of next generation sequencing in clinical primary immunodeficiencies.Retinol as a cofactor for PKCδ-mediated impairment of insulin sensitivity in a mouse model of diet-induced obesity Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance Knockout mouse models of insulin signaling: Relevance past and future Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease Genes associated with common variable immunodeficiency: one diagnosis to rule them all?Autoimmunity in Primary Antibody Deficiencies.Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.Protein kinase C as a tumor suppressor.Potentially Beneficial Effect of Hydroxychloroquine in a Patient with a Novel Mutation in Protein Kinase Cδ Deficiency.Epstein-Barr Virus-Specific Immune Control by Innate Lymphocytes.Editorial: entering the age of whole-exome sequencing in rheumatic diseases: novel insights into disease pathogenicity.Genetic heterogeneity of uncharacterized childhood autoimmune diseases with lymphoproliferation.Regulation of FcRγ function by site-specific serine phosphorylation.Protein kinase C: perfectly balanced.[Clinical immunology in rheumatology : State of the art].Reply Successful use of ofatumumab in two cases of early-onset juvenile SLE with thrombocytopenia caused by a mutation in protein kinase C δ

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Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans

http://www.wikidata.org/entity/Q36779397

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2013 nî lūn-bûn

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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Loss-of-function of the protei ...... oliferative syndrome in humans

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Loss-of-function of the protei ...... oliferative syndrome in humans

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Loss-of-function of the protei ...... oliferative syndrome in humans

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Loss-of-function of the protei ...... oliferative syndrome in humans

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Andreia Rangel-Santos

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Ashleigh A Hussey

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C Lucy Park

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Debra A Long Priel

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Douglas B Kuhns

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Hye Sun Kuehn

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Jennifer L Stoddard

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João B Oliveira

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Mingchang Zhang

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Moses O Evbuomwan

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P2860

Using biomarkers to predict the presence of FAS mutations in patients with features of the autoimmune lymphoproliferative syndrome

Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop

FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

Nodal and extranodal plasmacytomas expressing immunoglobulin a: an indolent lymphoproliferative disorder with a low risk of clinical progression

New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome

Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence.

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Julie E. Niemela

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235690691

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23430113

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3630827

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