Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.

Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.

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http://www.wikidata.org/entity/Q36788773
P2Y6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice.Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium.Bladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function.Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology.Nucleoside triphosphate diphosphohydrolase-1 ectonucleotidase is required for normal vas deferens contraction and male fertility through maintaining P2X1 receptor function.ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling.Receptors, channels, and signalling in the urothelial sensory system in the bladderControl of urinary drainage and voiding.Lack of specificity shown by P2Y6 receptor antibodies.Gene expression of muscarinic, tachykinin, and purinergic receptors in porcine bladder: comparison with cultured cells.Purinergic signalling in the urinary tract in health and disease.BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function.Purinergic Signalling: Therapeutic Developments.P2Y6 regulates cytoskeleton reorganization and cell migration of C2C12 myoblasts via ROCK pathway.
P2860

Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.

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http://www.wikidata.org/entity/Q36788773
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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name
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@ast
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@en
type
label
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@ast
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@en
prefLabel
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@ast
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Extracellular UDP enhances P2X ...... nositol trisphosphate pathway.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932