Kindlin-2 directly binds actin and regulates integrin outside-in signaling
about
The integrin adhesome network at a glanceOf Kindlins and CancerA proteomics view on integrin-mediated adhesions.Integrin-mediated mechanotransduction.Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis.Kindlin-2 interacts with endothelial adherens junctions to support vascular barrier integrity.The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.Optogenetic interrogation of integrin αVβ3 function in endothelial cells.The binding interface of kindlin-2 and ILK involves Asp344/Asp352/Thr356 in kindlin-2 and Arg243/Arg334 in ILK.Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation.Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin.Kindlin-2 Association with Rho GDP-Dissociation Inhibitor α Suppresses Rac1 Activation and Podocyte Injury.Structural basis of kindlin-mediated integrin recognition and activation.Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ.
P2860
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P2860
Kindlin-2 directly binds actin and regulates integrin outside-in signaling
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Kindlin-2 directly binds actin and regulates integrin outside-in signaling
@en
type
label
Kindlin-2 directly binds actin and regulates integrin outside-in signaling
@en
prefLabel
Kindlin-2 directly binds actin and regulates integrin outside-in signaling
@en
P2093
P2860
P356
P1476
Kindlin-2 directly binds actin and regulates integrin outside-in signaling
@en
P2093
Edward F Plow
Elzbieta Pluskota
Julia Vaynberg
Kamila Bledzka
Katarzyna Bialkowska
Khalid Sossey-Alaoui
P2860
P304
P356
10.1083/JCB.201501006
P407
P577
2016-04-04T00:00:00Z