The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
about
Drug Discovery Targeting Bromodomain-Containing Protein 4.Advancements in Developing Strategies for Sterilizing and Functional HIV Cures.Chemical probes targeting epigenetic proteins: Applications beyond oncology.Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1.Selective targeting of epigenetic reader domains.Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development.Cancer therapies in HIV cure research.Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential.Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui.The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells.BET inhibitors RVX-208 and PFI-1 reactivate HIV-1 from latency.BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-mesenchymal Transition.BI-2536 and BI-6727, dual Polo-like kinase/bromodomain inhibitors, effectively reactivate latent HIV-1.Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.HIV latency reversing agents act through Tat post translational modifications.Zinc-Finger Nucleases Induced by HIV-1 Tat Excise HIV-1 from the Host Genome in Infected and Latently Infected Cells.
P2860
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P2860
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@ast
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@en
type
label
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@ast
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@en
prefLabel
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@ast
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@en
P2093
P2860
P356
P1433
P1476
The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.
@en
P2093
Hanxian Zeng
Hongzhou Lu
Huanzhang Zhu
Junxiao Deng
Xinyi Yang
Yinzhong Shen
P2860
P2888
P356
10.1038/SREP24100
P407
P50
P577
2016-04-12T00:00:00Z
P5875
P6179
1045035897