Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
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Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype.CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestionPathogenesis of human immunodeficiency virus infectionCatalytic antibodies to HIV: physiological role and potential clinical utilityDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesStructural plasticity and conformational transitions of HIV envelope glycoprotein gp120Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 BindingSequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 BindingBurkholderia oklahomensisagglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activityStructure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyFine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via gp120 V3 interactionsHuman immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoproteinCharacterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoproteinElicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoproteinStructure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.Engineering antibody-like inhibitors to prevent and treat HIV-1 infection.Extreme sequence divergence but conserved ligand-binding specificity in Streptococcus pyogenes M proteinB cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding siteInfluence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primatesGenetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.Phenotype-associated env gene variation among eight related human immunodeficiency virus type 1 clones: evidence for in vivo recombination and determinants of cytotropism outside the V3 domain.Dissociation of the CD4 and CXCR4 binding properties of human immunodeficiency virus type 1 gp120 by deletion of the first putative alpha-helical conserved structure.Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions.Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity.Antigenic variation within the CD4 binding site of human immunodeficiency virus type 1 gp120: effects on chemokine receptor utilization.Virus isolates during acute and chronic human immunodeficiency virus type 1 infection show distinct patterns of sensitivity to entry inhibitors.Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events.Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoproteinHuman anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness.Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus.V3-specific neutralizing antibodies in sera from HIV-1 gp160-immunized volunteers block virus fusion and act synergistically with human monoclonal antibody to the conformation-dependent CD4 binding site of gp120. NIH-NIAID AIDS Vaccine Clinical TriaVertical Transmission of HIV-1. Correlation with maternal viral load and plasma levels of CD4 binding site anti-gp120 antibodiesA general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infantInfectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivo
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P2860
Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
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1990 nî lūn-bûn
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1990年の論文
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1990年論文
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1990年論文
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1990年論文
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name
Identification of individual h ...... rtant for CD4 receptor binding
@ast
Identification of individual h ...... rtant for CD4 receptor binding
@en
type
label
Identification of individual h ...... rtant for CD4 receptor binding
@ast
Identification of individual h ...... rtant for CD4 receptor binding
@en
prefLabel
Identification of individual h ...... rtant for CD4 receptor binding
@ast
Identification of individual h ...... rtant for CD4 receptor binding
@en
P2093
P2860
P1433
P1476
Identification of individual h ...... rtant for CD4 receptor binding
@en
P2093
P2860
P304
P407
P577
1990-12-01T00:00:00Z