Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: scarification vaccination
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Recombinant Ranaviruses for Studying Evolution of Host-Pathogen Interactions in Ectothermic VertebratesThe evolution of poxvirus vaccinesVaccinia-based influenza vaccine overcomes previously induced immunodominance hierarchy for heterosubtypic protection.Long term recall of memory CD8 T cells in mice to first and third generation smallpox vaccines.Use of a recombinant vaccinia virus expressing interferon gamma for post-exposure protection against vaccinia and ectromelia virusesDeletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.Comparative analysis of poxvirus orthologues of the vaccinia virus E3 protein: modulation of protein kinase R activity, cytokine responses, and virus pathogenicityVaccination with a Live Attenuated Cytomegalovirus Devoid of a Protein Kinase R Inhibitory Gene Results in Reduced Maternal Viremia and Improved Pregnancy Outcome in a Guinea Pig Congenital Infection Model.Antagonism of the protein kinase R pathway by the guinea pig cytomegalovirus US22-family gene gp145.Genomic Analysis, Phenotype, and Virulence of the Historical Brazilian Smallpox Vaccine Strain IOC: Implications for the Origins and Evolutionary Relationships of Vaccinia VirusUpdate on the current status of cytomegalovirus vaccines.The attenuated NYCBH vaccinia virus deleted for the immune evasion gene, E3L, completely protects mice against heterologous challenge with ectromelia virus.Attenuated NYCBH vaccinia virus deleted for the E3L gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaquesVaccinia virus vaccines: past, present and future.Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replicationThird-generation smallpox vaccines: challenges in the absence of clinical smallpox.The NYCBH vaccinia virus deleted for the innate immune evasion gene, E3L, protects rabbits against lethal challenge by rabbitpox virus.Deletion of virulence associated genes from attenuated African swine fever virus isolate OUR T88/3 decreases its ability to protect against challenge with virulent virus.Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory.Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox.
P2860
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P2860
Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: scarification vaccination
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Vaccinia viruses with mutation ...... nes: scarification vaccination
@en
type
label
Vaccinia viruses with mutation ...... nes: scarification vaccination
@en
prefLabel
Vaccinia viruses with mutation ...... nes: scarification vaccination
@en
P2093
P2860
P1433
P1476
Vaccinia viruses with mutation ...... nes: scarification vaccination
@en
P2093
Bertram L Jacobs
Carole R Baskin
Garilyn M Jentarra
Jeffrey O Langland
Jin Won Youn
Karen Kibler
Michael C Heck
Olga Ananieva
Yung Chang
P2860
P304
P356
10.1016/J.VACCINE.2008.03.044
P407
P577
2008-04-08T00:00:00Z