Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown
about
Fatty acid metabolism and the basis of brown adipose tissue functionMouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymesDefinition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1AThe cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitusCloning and characterization of the promoter for the liver isoform of the rat carnitine palmitoyltransferase I (L-CPT I) geneEvidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscleIdentification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibitionTopology of carnitine palmitoyltransferase I in the mitochondrial outer membraneInhibition by etomoxir of rat liver carnitine octanoyltransferase is produced through the co-ordinate interaction with two histidine residuesPig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivityExpression of novel isoforms of carnitine palmitoyltransferase I (CPT-1) generated by alternative splicing of the CPT-ibeta gene.Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissueElucidation of the mechanism by which (+)-acylcarnitines inhibit mitochondrial fatty acid transport.Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adLeptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake.The Origin and Diversity of Cpt1 Genes in Vertebrate Species.Elaidyl-sulfamide, an oleoylethanolamide-modelled PPARα agonist, reduces body weight gain and plasma cholesterol in rats.Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouseChange in expression of heart carnitine palmitoyltransferase I isoforms with electrical stimulation of cultured rat neonatal cardiac myocytes.Alterations in the carnitine cycle in a mouse model of Rett syndrome.GATA-4 and serum response factor regulate transcription of the muscle-specific carnitine palmitoyltransferase I beta in rat heart.Thyroid hormone regulates carnitine palmitoyltransferase Ialpha gene expression through elements in the promoter and first intron.Mammalian mitochondrial beta-oxidation.Cloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme.Expression of the rat liver carnitine palmitoyltransferase I (CPT-Ialpha) gene is regulated by Sp1 and nuclear factor Y: chromosomal localization and promoter characterization.Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues.Cytological evidence that the C-terminus of carnitine palmitoyltransferase I is on the cytosolic face of the mitochondrial outer membrane.Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity.Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation.Effect of L-carnitine supplementation on cardiac carnitine palmitoyltransferase activities and plasma carnitine concentrations in adriamycin-treated rats.Comparison of the catalytic activities of three isozymes of carnitine palmitoyltransferase 1 expressed in COS7 cells.Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research.Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation.Regulation of acetyl CoA carboxylase and carnitine palmitoyl transferase-1 in rat adipocytes.A low fat diet ameliorates pathology but retains beneficial effects associated with CPT1b knockout in skeletal muscle.Dramatic enhancement of the specific expression of the heart-type fatty acid binding protein in rat brown adipose tissue by cold exposure.Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat.
P2860
Q26744147-0EE530F2-8DAB-41BD-A32D-0EB3E15C8813Q28253454-B2C7B1C8-6A40-411B-9726-D72AD705DC52Q28298983-7B98AAB9-FCA2-4FB0-98D7-91376C27385DQ28344691-A0B49007-5029-4189-B2E8-1FC9F047B4F0Q28578201-87BDF708-CE0D-4759-9178-3BC1D1F66098Q28578207-979F9C61-F9ED-42F8-9037-3451C65CFD79Q28579126-37C01F53-FDC8-495A-8D65-A494E7E9F4F3Q28579497-DDCBD9F0-A80D-4EE1-97C2-FACB76F1C43CQ28581761-88A09B6D-6993-4254-B43A-C9D84EC84B06Q28582612-DCE9A188-E1B1-43F7-93D3-B76E38B630ADQ32043797-F1992FAC-F0E2-4665-A252-1D4DD6EA21DCQ33295358-7B622399-2757-483D-BAF1-5FF090752E6CQ33334930-7A9B7A72-15B0-429A-A498-534648625556Q34089543-49649C38-38C7-46D7-85B0-2A3FB8635A7AQ34706061-13A0A818-0BCC-4072-A80D-D30DC715C1AEQ35793233-5B64978B-4EB1-44E3-93D6-1CBF343A03C0Q36179973-A86E0210-BE82-4E3D-9787-64235CED720CQ36501934-51E6BB0D-EAEF-40DF-B238-1F7BCC5F8E2AQ36802855-5CF24C5C-FB44-47EA-A44C-B7EB21F9A844Q37620699-EAE0A1AF-46A4-4FED-8E82-7733EA784A35Q38307415-572DA367-8F73-4316-B906-8CD640677FB4Q40859169-C9DF37FE-DE19-49DE-9C29-3D08BD19F8F7Q41280085-3FCA5A88-BDD9-4530-B9E8-DD37D8E4A1F2Q41813303-BB147D01-67D2-4EFA-925E-B96F07028D10Q41833598-7572D672-E02D-490E-A10A-37E8D6986D42Q41920104-B82D26C3-EA08-46A0-BB69-4000AC4BFC26Q42994236-2CAD5E89-995E-43C5-98B4-B9C6D943894EQ42996947-C019E19D-5538-482C-97C9-31E1E8C5F3ADQ43616441-919390F7-4003-4B70-A2AD-2839E8A40873Q44350861-6E536CEA-362A-4D66-AE62-5967555AA98BQ45418153-4529DE3D-446C-4B03-B7A8-70CCDDF368C4Q46399354-0A913224-32C1-4C55-93DF-0E2565D33F3AQ46748005-C555988C-052A-443F-806B-087BEAC6CE0FQ46750263-BF99BFD3-84E1-40F3-8F96-A42286E6142BQ47116575-7D9F5FEB-3B8A-4273-A81D-89A59EF184E8Q48048350-BD65F025-136B-42F8-8C99-7208F0E82505Q54115482-4CC9E276-861E-4F20-AE63-E9DAB8714661
P2860
Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Expression of a cDNA isolated ...... h white (epididymal) and brown
@ast
Expression of a cDNA isolated ...... h white (epididymal) and brown
@en
type
label
Expression of a cDNA isolated ...... h white (epididymal) and brown
@ast
Expression of a cDNA isolated ...... h white (epididymal) and brown
@en
prefLabel
Expression of a cDNA isolated ...... h white (epididymal) and brown
@ast
Expression of a cDNA isolated ...... h white (epididymal) and brown
@en
P2093
P2860
P356
P1476
Expression of a cDNA isolated ...... h white (epididymal) and brown
@en
P2093
P2860
P304
P356
10.1074/JBC.271.12.6972
P407
P577
1996-03-01T00:00:00Z