Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.
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Role of Osteopontin in Liver DiseasesMicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signalingOsteopontin-A Master Regulator of Epithelial-Mesenchymal TransitionExtracellular matrix and liver diseaseHCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replication.New drug targets for alcoholic liver disease.Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis.The versatile functions of Sox9 in development, stem cells, and human diseasesEpimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in miceMicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells.MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.Osteopontin: Versatile modulator of liver diseases.Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives.Re-expression of pro-fibrotic, embryonic preserved mediators in irradiated arterial vessels of the head and neck region.Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment.Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas.Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice.Hepatic stellate cells as key target in liver fibrosis.Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress.PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.RNAi in murine hepatocytes: the agony of choice--a study of the influence of lipid-based transfection reagents on hepatocyte metabolism.Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytesOsteopontin: a new player in regulating hepatic ductular reaction and hepatic progenitor cell responses during chronic liver injury.Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies.SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.Notch signaling and progenitor/ductular reaction in steatohepatitis.Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.Role of canonical Hedgehog signaling pathway in liver
P2860
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P2860
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@ast
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@en
type
label
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@ast
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@en
prefLabel
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@ast
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@en
P2093
P2860
P50
P356
P1433
P1476
Osteopontin is a novel downstr ...... n of liver fibrosis in humans.
@en
P2093
Abed M Zaitoun
Andrew Berry
Andrew D Sharrocks
Brian J Thomson
Cliff Rowe
Derek A Mann
Emma Harvey
Fiona Oakley
Nicoletta Bobola
Varinder Athwal
P2860
P304
P356
10.1002/HEP.25758
P407
P577
2012-09-01T00:00:00Z