Sequence-specific DNA binding by the v-erbA oncogene protein of avian erythroblastosis virus
about
SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathwaysLarge-scale analysis by SAGE reveals new mechanisms of v-erbA oncogene action.Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alphaOntogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA functionThe erbA oncogene represses the actions of both retinoid X and retinoid A receptors but does so by distinct mechanisms.Association of v-ErbA with Smad4 disrupts TGF-beta signaling.Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire.Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes.Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.
P2860
Q30440069-9FAC18E7-0D09-401C-AF6D-8893590ED50AQ33233321-4782AF36-61FB-4176-BCBF-E763F0631257Q33303949-43CA672B-6139-4921-919D-C7E9DAAF0C4CQ36666829-8AD1BDEA-A6BD-4E88-AD3F-59CCF685BE38Q36684411-E4F2BE17-D763-4C95-8151-1484A91BAB5AQ36822461-51DB168F-A212-4768-9445-44B4FC3145B2Q37112637-D5EE5FEF-268C-44CA-8450-03CCB054F0C1Q37455473-FE798ED4-42B5-49DC-A8B7-4502DB94EA60Q40872478-41675F9F-B57D-49D7-BA11-AE8ADD30BBF3Q41079763-8EB0393D-99C7-489E-B06C-EFB9C49BD96BQ42663412-F5B33027-61C0-43D5-B662-E7A0B573EDA1
P2860
Sequence-specific DNA binding by the v-erbA oncogene protein of avian erythroblastosis virus
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@ast
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@en
type
label
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@ast
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@en
prefLabel
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@ast
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@en
P2860
P1433
P1476
Sequence-specific DNA binding ...... f avian erythroblastosis virus
@en
P2093
Privalsky ML
P2860
P304
P407
P577
1990-03-01T00:00:00Z