A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.
about
Telomerase Regulation from Beginning to the EndMany disease-associated variants of hTERT retain high telomerase enzymatic activityContributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.Telomerase enzymatic component hTERT shortens long telomeres in human cells.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.
P2860
A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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name
A translocation-defective telo ...... s and confers immortalization.
@ast
A translocation-defective telo ...... s and confers immortalization.
@en
type
label
A translocation-defective telo ...... s and confers immortalization.
@ast
A translocation-defective telo ...... s and confers immortalization.
@en
prefLabel
A translocation-defective telo ...... s and confers immortalization.
@ast
A translocation-defective telo ...... s and confers immortalization.
@en
P2860
P356
P1476
A translocation-defective telo ...... s and confers immortalization.
@en
P2093
Tsz Wai Chu
P2860
P304
P356
10.1091/MBC.E12-12-0889
P577
2013-02-27T00:00:00Z