Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.
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Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contractionLipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damagePerilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levelsCOPI complex is a regulator of lipid homeostasisInteractions of perilipin-5 (Plin5) with adipose triglyceride lipasePerilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidationActivation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteinsPerilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondriaComparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytesSkeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulationExpression profile of fatty acid metabolism genes in preimplantation blastocysts of obese and non-obese mice.The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage.Piecing together the puzzle of perilipin proteins and skeletal muscle lipolysis.Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.CIDE gene expression in adipose tissue, liver, and skeletal muscle from obese and lean pigsOntogeny of hepatic energy metabolism genes in mice as revealed by RNA-sequencingThe role of lipid droplets in metabolic disease in rodents and humans.Lipid droplets: size matters.Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP).Adipose differentiation-related protein regulates lipids and insulin in pancreatic isletsLipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.Identification of diverse lipid droplet targeting motifs in the PNPLA family of triglyceride lipasesHomozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscleUnique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated proteinPlin2 inhibits cellular glucose uptake through interactions with SNAP23, a SNARE complex proteinGCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat.Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.The metabolically benign and malignant fatty liver.Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingCytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol fluxIdentification of the major functional proteins of prokaryotic lipid droplets.FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotectionLiver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance in High Fat-Fed Mice.Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestrationOpposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation.Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis.Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes.In Situ Evaluation of Oxidative Stress in Rat Fatty Liver Induced by a Methionine- and Choline-Deficient Diet
P2860
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P2860
Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Consequences of lipid droplet ...... duction of insulin resistance.
@ast
Consequences of lipid droplet ...... duction of insulin resistance.
@en
type
label
Consequences of lipid droplet ...... duction of insulin resistance.
@ast
Consequences of lipid droplet ...... duction of insulin resistance.
@en
prefLabel
Consequences of lipid droplet ...... duction of insulin resistance.
@ast
Consequences of lipid droplet ...... duction of insulin resistance.
@en
P2093
P2860
P50
P356
P1433
P1476
Consequences of lipid droplet ...... nduction of insulin resistance
@en
P2093
Carole Sztalryd
Constantine Londos
Da-Wei Gong
Daozhan Yu
John C McLenithan
Rong-Zee Yang
P2860
P304
P356
10.2337/DB07-1383
P407
P577
2008-05-16T00:00:00Z