Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
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Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1STAT5 in hematopoietic stem cell biology and transplantationLipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver.In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2.Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice.Unbiased, genome-wide in vivo mapping of transcriptional regulatory elements reveals sex differences in chromatin structure associated with sex-specific liver gene expressionStat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Mapping the growth hormone--Stat5b--IGF-I transcriptional circuit.Hepatic microtubule acetylation and stability induced by chronic alcohol exposure impair nuclear translocation of STAT3 and STAT5B, but not Smad2/3.Suppression of signal transducers and activators of transcription 1 in hepatocellular carcinoma is associated with tumor progression.The hormonal action of IGF1 in postnatal mouse growth.Sex differences in the expression of hepatic drug metabolizing enzymes.Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.Bile acid-induced inflammatory signaling in mice lacking Foxa2 in the liver leads to activation of mTOR and age-onset obesity.Male-specific hepatic Bcl6: growth hormone-induced block of transcription elongation in females and binding to target genes inversely coordinated with STAT5Ethanol metabolism by alcohol dehydrogenase or cytochrome P450 2E1 differentially impairs hepatic protein trafficking and growth hormone signaling.Hepatic transcriptome profiling identifies differences in expression of genes associated with changes in metabolism and postnatal growth between Hereford and Holstein-Friesian bulls.The Role of Signal Transducer and Activator of Transcription 5 and Transforming Growth Factor-Beta 1 in Hepatic Fibrosis Induced by Chronic Hepatitis C Virus Infection in Egyptian Patients.Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancerHypermethylation of INS Promoter in the Developing Liver of Cattle
P2860
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P2860
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@ast
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@en
type
label
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@ast
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@en
prefLabel
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@ast
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@en
P2860
P1476
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
@en
P2093
Atsushi Hosui
Lothar Hennighausen
P2860
P304
P356
10.1152/PHYSIOLGENOMICS.00048.2008
P577
2008-05-06T00:00:00Z