Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. - Wikidata - wikimedia - TriplyDB

Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats.

Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats.

http://www.wikidata.org/entity/Q36809051

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Legal highs: staying on top of the flood of novel psychoactive substances Binge-like acquisition of 3,4-methylenedioxypyrovalerone (MDPV) self-administration and wheel activity in rats The preclinical pharmacology of mephedrone; not just MDMA by another name.Intravenous self-administration of entactogen-class stimulants in male rats Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs Use of synthetic cathinones and cannabimimetics among injection drug users in San Diego, California Cocaine self-administration in social dyads using custom-built operant conditioning chambers Predicting abuse potential of stimulants and other dopaminergic drugs: overview and recommendations Synthetic cathinones and their rewarding and reinforcing effects in rodents.Behavioral pharmacology of designer cathinones: a review of the preclinical literature 3,4-Methylenedioxypyrovalerone prevents while methylone enhances methamphetamine-induced damage to dopamine nerve endings: β-ketoamphetamine modulation of neurotoxicity by the dopamine transporter.The new stimulant designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity.Baths salts, spice, and related designer drugs: the science behind the headlines.The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue.Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats Neurotoxicity Induced by Mephedrone: An up-to-date Review.Mephedrone interactions with cocaine: prior exposure to the 'bath salt' constituent enhances cocaine-induced locomotor activation in rats.Intravenous self-administration of mephedrone, methylone and MDMA in female rats.Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats Mephedrone alters basal ganglia and limbic dynorphin systems.One day access to a running wheel reduces self-administration of D-methamphetamine, MDMA and methylone.Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats.In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats Differential effects of 3,4-methylenedioxypyrovalerone (MDPV) and 4-methylmethcathinone (mephedrone) in rats trained to discriminate MDMA or a d-amphetamine + MDMA mixture.The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats.Abuse-related and abuse-limiting effects of methcathinone and the synthetic "bath salts" cathinone analogs methylenedioxypyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats.Bath salts and synthetic cathinones: an emerging designer drug phenomenon.Neuronal extracellular signal-regulated kinase (ERK) activity as marker and mediator of alcohol and opioid dependence.Khat and synthetic cathinones: a review.Reinforcing Effects of Cathinone NPS in the Intravenous Drug Self-Administration Paradigm.Neurotoxicology of Synthetic Cathinone Analogs.Predicting the Abuse Liability of Entactogen-Class, New and Emerging Psychoactive Substances via Preclinical Models of Drug Self-administration.Clinical Pharmacology of the Synthetic Cathinone Mephedrone.Mephedrone, methylone and 3,4-methylenedioxypyrovalerone (MDPV) induce conditioned place preference in mice.Pharmacology should be at the centre of all preclinical and clinical studies on new psychoactive substances (recreational drugs).Patterns of use and toxicity of new para-halogenated substituted cathinones: 4-CMC (clephedrone), 4-CEC (4-chloroethcatinone) and 4-BMC (brephedrone).'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function.Locomotor Stimulant and Rewarding Effects of Inhaling Methamphetamine, MDPV, and Mephedrone via Electronic Cigarette-Type Technology.Is there any difference in patterns of use and psychiatric symptom status between injectors and non-injectors of mephedrone?Inhaled delivery of Δ(9)-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology.

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Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats.

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Addiction Biology

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Mephedrone (4-methylmethcathin ...... prague-Dawley and Wistar rats.

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Deborah J Barlow

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Deepshikha Angrish

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Karen L Houseknecht

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Kevin M Creehan

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M Jerry Wright

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Michael A Taffe

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Shawn M Aarde

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Sophia A Vandewater

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Tobin J Dickerson

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P2860

The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue

Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats

4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse

Pharmacological characterization of designer cathinones in vitro

Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats

Mephedrone, new kid for the chop?

Chiral gas chromatographic assay with flame ionization detection for amphetamine enantiomers in microsomal incubates.

Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats.

MDMA self-administration in rats: acquisition, progressive ratio responding and serotonin transporter binding.

In vitro metabolism studies on mephedrone and analysis of forensic cases.

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786-799

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10.1111/ADB.12038

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5

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18

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