Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression
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Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activityRegulation of Mutant p53 Protein ExpressionEmerging Roles of MicroRNAs in EGFR-Targeted Therapies for Lung CancerTumor suppressor p53 and its gain-of-function mutants in cancerMutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapymicroRNAs: short non-coding bullets of gain of function mutant p53 proteins.A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells.Perfluorooctane Sulfonate Induces Autophagy-Dependent Apoptosis through Spinster 1-Mediated lysosomal-Mitochondrial Axis and Impaired Mitophagy.Zn(II)-curc targets p53 in thyroid cancer cellsMutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processingmiR-27a-3p suppresses tumor metastasis and VM by down-regulating VE-cadherin expression and inhibiting EMT: an essential role for Twist-1 in HCC.BECN1s, a short splice variant of BECN1, functions in mitophagy.Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activityTP53 mutants in the tower of babel of cancer progression.Mutant p53 in cancer: new functions and therapeutic opportunities.The paradigm of mutant p53-expressing cancer stem cells and drug resistance.Mutant p53 exerts oncogenic effects through microRNAs and their target gene networks.The p53/miR-34 axis in development and disease.How Does p73 Cause Neuronal Defects?miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cellsMutant p53 regulates Dicer through p63-dependent and -independent mechanisms to promote an invasive phenotype.Functions of TAp63 and p53 in restraining the development of metastatic cancer.Exploiting the p53 Pathway for Therapy.Aggregate penetrance of genomic variants for actionable disorders in European and African Americans.p53-R273H upregulates neuropilin-2 to promote cell mobility and tumor metastasisCaffeine induces sustained apoptosis of human gastric cancer cells by activating the caspase‑9/caspase‑3 signalling pathway.The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex.The interplay between mutant p53 and the mevalonate pathway.Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.Regulation of proliferation and cell cycle by protein regulator of cytokinesis 1 in oral squamous cell carcinoma.MicroRNA-27a participates in the pathological process of depression in rats by regulating VEGFA.
P2860
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P2860
Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression
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2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@ast
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@en
type
label
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@ast
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@en
prefLabel
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@ast
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@en
P2093
P2860
P356
P1476
Mutant p53-R273H gains new fun ...... suppressing miR-27a expression
@en
P2093
P2860
P2888
P356
10.1038/CDDIS.2013.97
P577
2013-04-04T00:00:00Z
P5875
P6179
1035873288