BHRF1, the Epstein-Barr virus gene with homology to Bc12, is dispensable for B-lymphocyte transformation and virus replication
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Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?Complete nucleotide sequence of the rhesus lymphocryptovirus: genetic validation for an Epstein-Barr virus animal model.MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifsBok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family membersHerpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis.An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell deathStructural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1Epstein-Barr virus latent genesBH3 domains define selective inhibitory interactions with BHRF-1 and KSHV BCL-2The N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation.The Methylation Status and Expression of Epstein-Barr Virus Early Genes BARF1 and BHRF1 in Epstein-Barr Virus-Associated Gastric Carcinomas.Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice.Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latencyAntiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins.EBNA-LP associates with cellular proteins including DNA-PK and HA95.The genetic approach to the Epstein-Barr virus: from basic virology to gene therapy.Epstein-Barr virus lytic infection contributes to lymphoproliferative disease in a SCID mouse model.Molecular virology of Epstein-Barr virus.Persistent gamma-herpesvirus infections: what can we learn from an experimental mouse model?The essential role of evasion from cell death in cancer.Delay of vaccinia virus-induced apoptosis in nonpermissive Chinese hamster ovary cells by the cowpox virus CHOhr and adenovirus E1B 19K genes.Reducing the complexity of the transforming Epstein-Barr virus genome to 64 kilobase pairs.Epstein-Barr virus infection and bcl-2 proto-oncogene expression. Separate events in the pathogenesis of Hodgkin's disease?Glycoprotein 110, the Epstein-Barr virus homolog of herpes simplex virus glycoprotein B, is essential for Epstein-Barr virus replication in vivo.Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transductionThe Epstein-Barr virus glycoprotein 110 carboxy-terminal tail domain is essential for lytic virus replication.Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogeneThe ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type.A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or BakIdentification of the in vivo role of a viral bcl-2Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells.Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell deathAn Epstein-Barr virus with a 58-kilobase-pair deletion that includes BARF0 transforms B lymphocytes in vitroMolecular evolution of herpesviruses: genomic and protein sequence comparisons.An African swine fever virus gene with similarity to the proto-oncogene bcl-2 and the Epstein-Barr virus gene BHRF1Epstein-Barr virus recombinants from overlapping cosmid fragments.Mutants of Epstein-Barr virus with a selective marker disrupting the TP gene transform B cells and replicate normally in culture.The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential.
P2860
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P2860
BHRF1, the Epstein-Barr virus gene with homology to Bc12, is dispensable for B-lymphocyte transformation and virus replication
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
BHRF1, the Epstein-Barr virus ...... ormation and virus replication
@en
type
label
BHRF1, the Epstein-Barr virus ...... ormation and virus replication
@en
prefLabel
BHRF1, the Epstein-Barr virus ...... ormation and virus replication
@en
P2093
P2860
P1433
P1476
BHRF1, the Epstein-Barr virus ...... ormation and virus replication
@en
P2093
P2860
P304
P407
P577
1991-11-01T00:00:00Z