Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme.
about
Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cellsN-terminal polyubiquitination and degradation of the Arf tumor suppressorTranslational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshiftDimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilinsDeterminants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrateX-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibilityStructural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive EvolutionPolyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizymeSUG1, a component of the 26 S proteasome, is an ATPase stimulated by specific RNAs.Yeast antizyme mediates degradation of yeast ornithine decarboxylase by yeast but not by mammalian proteasome: new insights on yeast antizyme.The Proteasome Subunit Rpn8 Interacts with the Small Nucleolar RNA Protein (snoRNP) Assembly Protein Pih1 and Mediates Its Ubiquitin-independent Degradation in Saccharomyces cerevisiae.Polyamines regulate both transcription and translation of the gene encoding ornithine decarboxylase antizyme in mouseAntizyme2 is a negative regulator of ornithine decarboxylase and polyamine transportStructural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylaseA unified pathway for the degradation of ornithine decarboxylase in reticulocyte lysate requires interaction with the polyamine-induced protein, ornithine decarboxylase antizymeMouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activityUbiquitin-independent proteasomal degradationGeneration of destabilized green fluorescent protein as a transcription reporterBiochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolyticaCloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylaseIron regulates the intracellular degradation of iron regulatory protein 2 by the proteasomeSubcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymesStructural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongationCritical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor.The ornithine decarboxylase gene of Caenorhabditis elegans: cloning, mapping and mutagenesis.Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuitFunctional roles of the dimer-interface residues in human ornithine decarboxylase.Determinants of the differential antizyme-binding affinity of ornithine decarboxylaseStudies on the regulation of ornithine decarboxylase in yeast: effect of deletion in the MEU1 gene.Yeast ornithine decarboxylase and antizyme form a 1:1 complex in vitro: purification and characterization of the inhibitory complexGly387 of murine ornithine decarboxylase is essential for the formation of stable homodimers.Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting.Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells.Amino acids regulate expression of antizyme-1 to modulate ornithine decarboxylase activityCloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain.Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1.Identification, cloning, and nucleotide sequencing of the ornithine decarboxylase antizyme gene of Escherichia coliKnockdown of antizyme inhibitor decreases prostate tumor growth in vivoUbiquitin dependent and independent protein degradation in the regulation of cellular polyamines.
P2860
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P2860
Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Regulated degradation of ornit ...... ne-inducible protein antizyme.
@en
type
label
Regulated degradation of ornit ...... ne-inducible protein antizyme.
@en
prefLabel
Regulated degradation of ornit ...... ne-inducible protein antizyme.
@en
P2860
P356
P1476
Regulated degradation of ornit ...... ne-inducible protein antizyme.
@en
P2860
P304
P356
10.1128/MCB.12.8.3556
P407
P577
1992-08-01T00:00:00Z