Combined transgenic expression of alpha-galactosidase and alpha1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galalpha(1,3)Gal.
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Immune modulation in xenotransplantationCarbohydrate recognition by boronolectins, small molecules, and lectins.Gene therapy in transplantation.Potential use of genetically modified pigs as organ donors for transplantation into humans.Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejectionPharmacotherapeutic agents in xenotransplantation.Double transgenic pigs with combined expression of human α1,2-fucosyltransferase and α-galactosidase designed to avoid hyperacute xenograft rejectionEfficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation.The pig as a source of cardiac xenografts.The immunological hurdles to cardiac xenotransplantation.The current state of xenotransplantationReducing Gal expression on the pig organ - a retrospective review.Carrageenan induces cell cycle arrest in human intestinal epithelial cells in vitro.Transgenic pigs designed to express human α-galactosidase to avoid humoral xenograft rejectionWill xenotransplantation ever be feasible?Enzymatic removal of alphaGal antigen in pig kidneys by ex vivo and in vivo administration of endo-beta-galactosidase C.Adenovirus-mediated expression of pig alpha(1, 3) galactosyltransferase reconstructs Gal alpha(1, 3) gal epitope on the surface of human tumor cells.Xenotransfusions, past and present.Carrageenan-induced innate immune response is modified by enzymes that hydrolyze distinct galactosidic bonds.Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cellsCarrageenan-induced NFkappaB activation depends on distinct pathways mediated by reactive oxygen species and Hsp27 or by Bcl10.Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.Pig xenogeneic antigen modification with green coffee bean alpha-galactosidase.Brief report: a new profile of terminal N-acetyllactosamines glycans on pig red blood cells and different expression of alpha-galactose on Sika deer red blood cells and nucleated cells.Viral vector-mediated delivery of competing glycosyltransferases modifies epitope expression cell specifically.Fetal porcine thymus engraftment, survival and CD4 reconstitution in alphaGal-KO mice is impaired in the presence of high levels of antibodies against alphaGal.Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research.Carbohydrate BiomarkersClustered Regularly Interspaced Short Palindromic Repeats/Cas9 Gene Editing Technique in Xenotransplantation
P2860
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P2860
Combined transgenic expression of alpha-galactosidase and alpha1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galalpha(1,3)Gal.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Combined transgenic expression ...... xenoepitope Galalpha(1,3)Gal.
@en
type
label
Combined transgenic expression ...... xenoepitope Galalpha(1,3)Gal.
@en
prefLabel
Combined transgenic expression ...... xenoepitope Galalpha(1,3)Gal.
@en
P2093
P2860
P356
P1476
Combined transgenic expression ...... xenoepitope Galalpha(1,3)Gal.
@en
P2093
Desnick RJ
Ioannou YA
McKenzie IF
Ostenried K
Sandrin MS
P2860
P304
14677-14682
P356
10.1073/PNAS.94.26.14677
P407
P577
1997-12-01T00:00:00Z