Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. - Wikidata - wikimedia - TriplyDB

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

http://www.wikidata.org/entity/Q36835706

about

Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast Cancer Environmental Influences on Genomic Imprinting Blood-based DNA methylation as biomarker for breast cancer: a systematic review Recurrent epimutations activate gene body promoters in primary glioblastoma Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke Environmental chemical exposures and human epigenetics High resolution profiling of human exon methylation by liquid hybridization capture-based bisulfite sequencing.Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells.DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.Evaluation of allelic expression of imprinted genes in adult human blood.No evidence for copy number and methylation variation in H19 and KCNQ10T1 imprinting control regions in children born small for gestational age.A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.IGF2/H19 hypomethylation in a patient with very low birthweight, preocious pubarche and insulin resistance.Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region.Leukocyte DNA as surrogate for the evaluation of imprinted Loci methylation in mammary tissue DNA.Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists Aberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancer Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status.Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma.Association of genomic instability, and the methylation status of imprinted genes and mismatch-repair genes, with neural tube defects.Methylation levels at imprinting control regions are not altered with ovulation induction or in vitro fertilization in a birth cohort Dietary factors, genetic and epigenetic influences in colorectal cancer.Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker.Loss of imprinting of IGF2 and the epigenetic progenitor model of cancer Pyrosequencing for accurate imprinted allele expression analysis The prevalence of loss of imprinting of H19 and IGF2 at birth.Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients.Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer.Possible roles of insulin, IGF-1 and IGFBPs in initiation and progression of colorectal cancer.Molecular mechanisms of genomic imprinting and clinical implications for cancer.Insulin and IGFs in obesity-related breast cancer.DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment.Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation.Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer.

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P2860

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

http://www.wikidata.org/entity/Q36835706

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

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type

label

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

@en

prefLabel

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

@en

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P1433

Human Molecular Genetics

P1476

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.

@en

P2093

Ana-Luisa Silva

http://www.w3.org/2001/XMLSchema#string

Ashraf E K Ibrahim

http://www.w3.org/2001/XMLSchema#string

Elena Klenova

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Gudrun Moore

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Joanna E Huddleston

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Kathryn Woodfine

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Maja Jagodic

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Manjinder S Sandhu

http://www.w3.org/2001/XMLSchema#string

Raffaella Nativio

http://www.w3.org/2001/XMLSchema#string

Santiago Uribe-Lewis

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P2860

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites

Biallelic expression of the H19 and IGF2 genes in hepatocellular carcinoma

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

Randomised study of screening for colorectal cancer with faecal-occult-blood test

Genomic imprinting: parental influence on the genome

P304

2633-2643

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scholarly article

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10.1093/HMG/DDN163

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P433

17

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P478

17

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James D Brenton

Ana-Teresa Maia

Paul D P Pharoah

P577

2008-06-09T00:00:00Z

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P5875

5315062

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P698

18541649

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colorectal cancer

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2515372

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