Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
about
Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and diseaseGenomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerEnvironmental Influences on Genomic ImprintingBlood-based DNA methylation as biomarker for breast cancer: a systematic reviewRecurrent epimutations activate gene body promoters in primary glioblastomaGender-specific methylation differences in relation to prenatal exposure to cigarette smokeEnvironmental chemical exposures and human epigeneticsHigh resolution profiling of human exon methylation by liquid hybridization capture-based bisulfite sequencing.Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells.DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.Evaluation of allelic expression of imprinted genes in adult human blood.No evidence for copy number and methylation variation in H19 and KCNQ10T1 imprinting control regions in children born small for gestational age.A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.IGF2/H19 hypomethylation in a patient with very low birthweight, preocious pubarche and insulin resistance.Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosisAlcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region.Leukocyte DNA as surrogate for the evaluation of imprinted Loci methylation in mammary tissue DNA.Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells.Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonistsAberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancerEpigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status.Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma.Association of genomic instability, and the methylation status of imprinted genes and mismatch-repair genes, with neural tube defects.Methylation levels at imprinting control regions are not altered with ovulation induction or in vitro fertilization in a birth cohortDietary factors, genetic and epigenetic influences in colorectal cancer.Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker.Loss of imprinting of IGF2 and the epigenetic progenitor model of cancerPyrosequencing for accurate imprinted allele expression analysisThe prevalence of loss of imprinting of H19 and IGF2 at birth.Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients.Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growthInsulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer.Possible roles of insulin, IGF-1 and IGFBPs in initiation and progression of colorectal cancer.Molecular mechanisms of genomic imprinting and clinical implications for cancer.Insulin and IGFs in obesity-related breast cancer.DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment.Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation.Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer.
P2860
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P2860
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
@en
type
label
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
@en
prefLabel
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
@en
P2093
P2860
P50
P356
P1476
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
@en
P2093
Ana-Luisa Silva
Ashraf E K Ibrahim
Elena Klenova
Gudrun Moore
Joanna E Huddleston
Kathryn Woodfine
Maja Jagodic
Manjinder S Sandhu
Raffaella Nativio
Santiago Uribe-Lewis
P2860
P304
P356
10.1093/HMG/DDN163
P577
2008-06-09T00:00:00Z