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The cellular and physiological functions of the Lowe syndrome protein OCRL1Phosphoinositides: tiny lipids with giant impact on cell regulationOCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates.Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening.Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia.Primary cilia signaling mediates intraocular pressure sensation.Ciliopathies: the trafficking connection.Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe.The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.Flow stimulated endocytosis in the proximal tubule.Digenic mutations of human OCRL paralogs in Dent's disease type 2 associated with Chiari I malformation.Inositol lipid phosphatases in membrane trafficking and human disease.Dopaminergic signaling within the primary cilia in the renovascular system.Ion transport in the zebrafish kidney from a human disease angle: possibilities, considerations, and future perspectives.VAMP7 modulates ciliary biogenesis in kidney cells.The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2.Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafishLowe syndrome: Between primary cilia assembly and Rac1-mediated membrane remodeling.Primary Cilium-Dependent Signaling Mechanisms.Primary cilia proteins: ciliary and extraciliary sites and functions.Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome.Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells.Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex.OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
OCRL1 modulates cilia length in renal epithelial cells.
@en
type
label
OCRL1 modulates cilia length in renal epithelial cells.
@en
prefLabel
OCRL1 modulates cilia length in renal epithelial cells.
@en
P2093
P2860
P1433
P1476
OCRL1 modulates cilia length in renal epithelial cells
@en
P2093
Lisa M Satlin
Lisa M Swanhart
Marcelo Carattino
Neil A Hukriede
Ora A Weisz
Rajeev Rohatgi
Shanshan Cui
Youssef Rbaibi
P2860
P304
P356
10.1111/J.1600-0854.2012.01387.X
P577
2012-07-04T00:00:00Z