On the structure of the N-terminal domain of the MscL channel: helical bundle or membrane interface
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Mechanical properties of lipid bilayers and regulation of mechanosensitive function: from biological to biomimetic channelsThe role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channelsDihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel PoreA reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulatorsThe oligomeric state of the truncated mechanosensitive channel of large conductance shows no variance in vivoS. aureus MscL is a pentamer in vivo but of variable stoichiometries in vitro: implications for detergent-solubilized membrane proteinsForce transduction and lipid binding in MscL: a continuum-molecular approachStructural investigation of MscL gating using experimental data and coarse grained MD simulationsAn improved open-channel structure of MscL determined from FRET confocal microscopy and simulationAn in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel.Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1: comparisons with structural modelsThe mechanosensitive channel of small conductance (MscS) functions as a Jack-in-the boxMutations in a Conserved Domain of E. coli MscS to the Most Conserved Superfamily Residue Leads to Kinetic Changes.Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.Three routes to modulate the pore size of the MscL channel/nanovalveMechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion.Sensing and responding to membrane tension: the bacterial MscL channel as a model system.The MscS and MscL families of mechanosensitive channels act as microbial emergency release valves.The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interfaceImproving the Design of a MscL-Based Triggered Nanovalve.Phosphatidylinositol is crucial for the mechanosensitivity of Mycobacterium tuberculosis MscLAn open-pore structure of the mechanosensitive channel MscL derived by determining transmembrane domain interactions upon gatingDynamics of protein-protein interactions at the MscL periplasmic-lipid interface.Mechanosensitivity of ion channels based on protein-lipid interactions.Nanomechanical properties of MscL α helices: A steered molecular dynamics studyFunctional similarities between heterogeneously and homogenously expressed MscL constructs.A cytoplasmic helix is required for pentamer formation of the Escherichia coli MscL mechanosensitive channel.Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve.Toward a structural blueprint for bilayer-mediated channel mechanosensitivity.Structural Dynamics of the MscL C-terminal Domain.Gating mechanism of mechanosensitive channel of large conductance: a coupled continuum mechanical-continuum solvation approach.Transmembrane TM3b of Mechanosensitive Channel MscS Interacts With Cytoplasmic Domain Cyto-Helix
P2860
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P2860
On the structure of the N-terminal domain of the MscL channel: helical bundle or membrane interface
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
On the structure of the N-term ...... l bundle or membrane interface
@en
type
label
On the structure of the N-term ...... l bundle or membrane interface
@en
prefLabel
On the structure of the N-term ...... l bundle or membrane interface
@en
P2093
P2860
P1433
P1476
On the structure of the N-term ...... l bundle or membrane interface
@en
P2093
Irene Iscla
Paul Blount
Robin Wray
P2860
P304
P356
10.1529/BIOPHYSJ.107.127423
P407
P577
2008-05-30T00:00:00Z