Multiple myeloma: a prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment.
about
Mechanism of action of lenalidomide in hematological malignanciesClonogenic multiple myeloma progenitors, stem cell properties, and drug resistanceComputational modeling of interactions between multiple myeloma and the bone microenvironmentBiomimetic tumor microenvironment on a microfluidic platformEx-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapyEffects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cellsLenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications.Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemiaInhibitor of apoptosis proteins as therapeutic targets in multiple myeloma.Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsLenalidomide induces immunomodulation in chronic lymphocytic leukemia and enhances antitumor immune responses mediated by NK and CD4 T cells.Cancer stem cells: controversies in multiple myelomaAnti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myelomaMechanism of immunomodulatory drugs' action in the treatment of multiple myeloma.Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activityExpanding role of lenalidomide in hematologic malignanciesMass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma.A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice.Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft modelInteractions of the Hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib.Increased circulating VCAM-1 correlates with advanced disease and poor survival in patients with multiple myeloma: reduction by post-bortezomib and lenalidomide treatment.From the bench to the bedside: emerging new treatments in multiple myeloma.Treatment of plasma cell dyscrasias with lenalidomide.Prognostic significance of absolute lymphocyte count/absolute monocyte count ratio at diagnosis in patients with multiple myeloma.Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization.Mechanism of action of immunomodulatory agents in multiple myeloma.Can we change the disease biology of multiple myeloma?Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy.The hemopoietic stem cell niche versus the microenvironment of the multiple myeloma-tumor initiating cell.Reelin promotes adhesion of multiple myeloma cells to bone marrow stromal cells via integrin β1 signaling.Bone marrow microenvironment-derived signals induce Mcl-1 dependence in multiple myeloma.3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma.Impact of XIAP protein levels on the survival of myeloma cellsClonal Expansion and Interrelatedness of Distinct B-Lineage Compartments in Multiple Myeloma Bone Marrow.Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma.Perspective: A model disease.Chondroitin sulfate proteoglycan serglycin influences protein cargo loading and functions of tumor-derived exosomes.Tumor-associated macrophages as a prognostic parameter in multiple myeloma.
P2860
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P2860
Multiple myeloma: a prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Multiple myeloma: a prototypic ...... their local microenvironment.
@en
type
label
Multiple myeloma: a prototypic ...... their local microenvironment.
@en
prefLabel
Multiple myeloma: a prototypic ...... their local microenvironment.
@en
P2093
P2860
P356
P1476
Multiple myeloma: a prototypic ...... their local microenvironment.
@en
P2093
Constantine S Mitsiades
Nicholas S Mitsiades
Nikhil C Munshi
P2860
P304
P356
10.1002/JCB.21213
P577
2007-07-01T00:00:00Z