Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons
about
Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesisMaintenance of postmitotic neuronal cell identityDistinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish modelsTargeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract developmentSequential requirement of Sox4 and Sox11 during development of the sympathetic nervous systemFrizzled3 is required for neurogenesis and target innervation during sympathetic nervous system developmentCo-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma.Genetic model system studies of the development of the enteric nervous system, gut motility and Hirschsprung's diseaseAnalysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivativesHand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis.Cytokines inhibit norepinephrine transporter expression by decreasing Hand2Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crestTargeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis.Enteric neuronal density contributes to the severity of intestinal inflammationA Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis.TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1.A twist of insight - the role of Twist-family bHLH factors in development.The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons.Autonomic cardiac innervation: development and adult plasticity.Transcriptional control of differentiation and neurogenesis in autonomic ganglia.Ontogeny of cardiac sympathetic innervation and its implications for cardiac disease.Choices choices: regulation of precursor differentiation during enteric nervous system development.Signaling molecules and transcription factors involved in the development of the sympathetic nervous system, with special emphasis on the superior cervical ganglion.Segregation of neuronal and neuroendocrine differentiation in the sympathoadrenal lineage.The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal deathIn vivo calcium dynamics during neural crest cell migration and patterning using GCaMP3.Prox1 identifies proliferating neuroblasts and nascent neurons during neurogenesis in sympathetic ganglia.Distinct roles of hand2 in developing and adult autonomic neurons.Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks during Development.From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development.Sympathetic tales: subdivisons of the autonomic nervous system and the impact of developmental studies
P2860
Q24596162-6A8A869F-D9AC-49FF-9730-D6242D1646DAQ27010931-F60EC0B8-4367-41B7-9EB6-DCFDB2421FDDQ27322622-969F41D7-B1E5-4D04-A78A-CE1C75ECE143Q28506655-296EDE14-E6A3-4502-9C06-1D026CDFD49DQ28571666-8B11D9E1-30AD-4FE2-9BE9-D3D65E78A572Q28588216-06C6AD0D-50C0-4A54-8FB7-E0883C2F7DC8Q33427209-50647D5B-1225-48AC-BE19-C2B4B51908B8Q33699347-32CC8204-3588-4494-A4BB-324018CA32CFQ34247181-72C6BF00-79F6-4B51-BC4B-B1FF8F987540Q34341687-E3CE065B-E687-457A-8814-A1E154D605B6Q34612857-E6951457-C207-4045-88C5-BE737157B231Q34650000-28A81B14-7FC4-41E1-B9E0-06331B4DE539Q35306096-4F1AEECD-5BBE-4C0D-8530-6C25CA210029Q35694738-57E710F2-8978-4692-A916-6F53407BFD19Q35882673-54CB2457-4969-4A6A-B1C1-43193A867B91Q36355188-13041EA3-9BED-40F8-B29D-5C09A61F1498Q37332873-7DA5F942-0431-466D-B182-3EAD65C44357Q37352684-CF6FFA28-3C26-4F7A-97EB-AD9EC2A8E145Q37496525-95A4A852-50B6-4A46-BF37-54DCA381B860Q37958900-7E487B95-17D0-49B2-B2D4-FDEBC8EE6EAFQ37991193-C32385F6-831D-490D-BEB1-5125A7EC6087Q38103291-352CE12C-7A79-4F2D-BB26-7A71AF6DC5EDQ38207506-B7E41916-6BCB-4324-961A-88D125A95369Q38231221-1089B118-FBB9-4109-B406-F628A22E6B91Q38315781-2B8E056C-CF7E-4354-B68E-37F1C6C3593AQ38809995-745E38D1-0746-492A-B2CF-C14942E46BAEQ42214317-E580A5AA-DF8E-4F2D-BF7A-197BB84DD1FDQ48273480-2A66F17C-B71E-40CB-9C9D-E4C931271451Q48946221-C4137581-207A-44F6-97CC-D5D9454A3DD8Q49787423-02C09230-FBAD-48BB-911C-EB3893D03426Q50426412-6AB38938-6D16-4324-A619-5F4D6465BE81Q58743516-A7A669F7-B459-43A6-8BA9-C4B26D8FAF6F
P2860
Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Conditional deletion of Hand2 ...... c sympathetic ganglion neurons
@en
type
label
Conditional deletion of Hand2 ...... c sympathetic ganglion neurons
@en
prefLabel
Conditional deletion of Hand2 ...... c sympathetic ganglion neurons
@en
P2093
P2860
P1476
Conditional deletion of Hand2 ...... c sympathetic ganglion neurons
@en
P2093
David E Clouthier
Douglas L Pittman
Eva Coppola
Hongbin Liu
Iain T Shepherd
Marthe J Howard
Tyler J Hendershot
P2860
P304
P356
10.1016/J.YDBIO.2008.03.036
P407
P577
2008-04-08T00:00:00Z