Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival. - Wikidata - wikimedia - TriplyDB

Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival.

Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival.

http://www.wikidata.org/entity/Q36839423

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Tumor Budding: The Name is EMT. Partial EMT Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?EMT and MET: necessary or permissive for metastasis?New insights into the role of EMT in tumor immune escape.Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes.Stability of the hybrid epithelial/mesenchymal phenotype.ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT OVOL guides the epithelial-hybrid-mesenchymal transition.ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program BRD7 Acts as a Tumor Suppressor Gene in Lung Adenocarcinoma.Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer Metastasis.Coupling the modules of EMT and stemness: A tunable 'stemness window' model Combinatorial treatment using targeted MEK and SRC inhibitors synergistically abrogates tumor cell growth and induces mesenchymal-epithelial transition in non-small-cell lung carcinoma.Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome.MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer.Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space.Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer.Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.Modeling continuum of epithelial mesenchymal transition plasticity.Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells Pharmacological and immunological targeting of tumor mesenchymalization.Targeting the Epithelial-to-Mesenchymal Transition: The Case for Differentiation-Based Therapy.Emerging Biological Principles of Metastasis.Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-to-mesenchymal transition in lung cancer.ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion.Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1.Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines.Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling.Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric.In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer.MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway.Epithelial-mesenchymal transition and inflammation at the site of the primary tumor.Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells.Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer.

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P2860

Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival.

http://www.wikidata.org/entity/Q36839423

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2015年论文

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Molecular portraits of epithel ...... d their relevance to survival.

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Molecular portraits of epithel ...... d their relevance to survival.

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Molecular portraits of epithel ...... d their relevance to survival.

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Molecular portraits of epithel ...... nd their relevance to survival

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Alice Chin

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Carmen Behrens

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Chee-Hong Wong

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Chenchen Yang

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Evan M Kroh

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Hong Wang

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Ignacio I Wistuba

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Ite A Laird-Offringa

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Jaime Rodriguez

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P2860

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination

miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells

Lung cancer signatures in plasma based on proteome profiling of mouse tumor models

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

The basics of epithelial-mesenchymal transition

Epithelial-mesenchymal transitions in tumour progression

Epithelial-mesenchymal transitions in development and disease

Molecular definition of breast tumor heterogeneity

A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)

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