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Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

http://www.wikidata.org/entity/Q36840001

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Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic rats Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease Implications of GABAergic Neurotransmission in Alzheimer's Disease Elusive roles for reactive astrocytes in neurodegenerative diseases Kinetic study of benzyl [1-14C]acetate as a potential probe for astrocytic energy metabolism in the rat brain: Comparison with benzyl [2-14C]acetate.Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study.In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy.In vivo imaging of tau pathology using multi-parametric quantitative MRI.The Tau/A152T mutation, a risk factor for frontotemporal-spectrum disorders, leads to NR2B receptor-mediated excitotoxicity.Anesthesia and tau pathology.Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study.Neurotoxic saboteurs: straws that break the hippo's (hippocampus) back drive cognitive impairment and Alzheimer's Disease.Protein phosphorylation in neurodegeneration: friend or foe?Metabolic Modifications in Human Biofluids Suggest the Involvement of Sphingolipid, Antioxidant, and Glutamate Metabolism in Alzheimer's Disease Pathogenesis.Mitochondrial function in ageing: coordination with signalling and transcriptional pathways.Frontotemporal Lobar Degeneration: Mechanisms and Therapeutic Strategies.Increased astroglial activity and reduced neuronal function across brain in AβPP-PS1 mouse model of Alzheimer's disease.Energy metabolism and inflammation in brain aging and Alzheimer's disease.Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation.Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation.Towards a Better Understanding of GABAergic Remodeling in Alzheimer's Disease.Differential effects of ethanol on regional glutamatergic and GABAergic neurotransmitter pathways in mouse brain.Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's Disease.Diversity of astroglial responses across human neurodegenerative disorders and brain aging.Astrocyte and Alzheimer's disease.In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse model

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Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

http://www.wikidata.org/entity/Q36840001

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

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type

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Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

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prefLabel

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

@en

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P1433

Journal of Cerebral Blood Flow & Metabolism

P1476

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

@en

P2093

Linn Hege Nilsen

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Ursula Sonnewald

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P2860

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Tau filament formation in transgenic mice expressing P301L tau.

Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex.

Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17).

MRS in presymptomatic MAPT mutation carriers: a potential biomarker for tau-mediated pathology

Reduced hippocampal glutamate in Alzheimer disease.

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

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684-691

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scholarly article

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10.1038/JCBFM.2012.212

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5

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33

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Caroline D. Rae

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2013-01-23T00:00:00Z

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235337776

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