PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers
about
Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathwaysErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor.Addition of the p110α inhibitor BYL719 overcomes targeted therapy resistance in cells from Her2-positive-PTEN-loss breast cancer.Solasodine inhibits human colorectal cancer cells through suppression of the AKT/glycogen synthase kinase-3β/β-catenin pathway.Protein Kinase Targets in Breast Cancer.Novel treatment strategies for patients with HER2-positive breast cancer who do not benefit from current targeted therapy drugs
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P2860
PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
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2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
PI3K-p110α mediates resistance ...... PTEN-deficient breast cancers
@en
type
label
PI3K-p110α mediates resistance ...... PTEN-deficient breast cancers
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prefLabel
PI3K-p110α mediates resistance ...... PTEN-deficient breast cancers
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P2093
P2860
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P1476
PI3K-p110α mediates resistance ...... PTEN-deficient breast cancers
@en
P2093
J M Spangle
T M Roberts
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P2888
P304
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10.1038/ONC.2015.406
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P577
2015-10-26T00:00:00Z