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The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cellsA broad role for the zinc finger protein ZNF202 in human lipid metabolismThe von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1PAX 8 regulates human WT1 transcription through a novel DNA binding siteDespite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteinsMutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.WT1 gene expression as a prognostic marker in advanced serous epithelial ovarian carcinoma: an immunohistochemical study.An Sp1/Sp3 binding polymorphism confers methylation protection.TGF-β-activated kinase 1 is crucial in podocyte differentiation and glomerular capillary formation.Krüppel -like factor 8 is a stress-responsive transcription factor that regulates expression of HuR.Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene.Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1TGF-beta1 reduces Wilms' tumor suppressor gene expression in podocytes.miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level.A mutant Ahr allele protects the embryonic kidney from hydrocarbon-induced deficits in fetal programming.Transcription factor Sp3 knockout mice display serious cardiac malformations.Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes.The polycystic kidney disease-1 promoter is a target of the beta-catenin/T-cell factor pathway.Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2).The role of NF-kappaB in the regulation of the expression of wilms tumor suppressor gene WT1.Sp3 regulates fas expression in lung epithelial cellsActivation of the WT1 tumor suppressor gene promoter by Pea3.Overlapping DNA recognition motifs between Sp1 and a novel trans-acting factor within the wt1 tumour suppressor gene promoter.Transcription factor specificity protein 1 (SP1) and activating protein 2alpha (AP-2alpha) regulate expression of human KCTD10 gene by binding to proximal region of promoter.The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity.Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer.Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter.Genes for the human mitochondrial trifunctional protein alpha- and beta-subunits are divergently transcribed from a common promoter region.Characterization of multiple enhancer regions upstream of the apolipoprotein(a) gene.Transcription factor Sp1 expression is upregulated in human glomerulonephritis: correlation with pSmad2/3 and p300 expression and renal injury.Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome.Using directed information to build biologically relevant influence networks.Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1.Inhibitory mechanism of pure curcumin on Wilms' tumor 1 (WT1) gene expression through the PKCα signaling pathway in leukemic K562 cells.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Sp1 is a critical regulator of the Wilms' tumor-1 gene.
@en
type
label
Sp1 is a critical regulator of the Wilms' tumor-1 gene.
@en
prefLabel
Sp1 is a critical regulator of the Wilms' tumor-1 gene.
@en
P2093
P2860
P356
P1476
Sp1 is a critical regulator of the Wilms' tumor-1 gene.
@en
P2093
P2860
P304
P356
10.1074/JBC.272.5.2901
P407
P577
1997-01-01T00:00:00Z