Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia - Wikidata - wikimedia - TriplyDB

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

http://www.wikidata.org/entity/Q36843780

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Clinical implications of the molecular genetics of chronic lymphocytic leukemia The biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemia Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.Republished: Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks.Genetic abnormalities in chronic lymphocytic leukemia: where we are and where we go Evidences showing wide presence of small genomic aberrations in chronic lymphocytic leukemia NF1 inactivation in adult acute myelogenous leukemia Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy.A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia.The prognostic significance of various 13q14 deletions in chronic lymphocytic leukemia.Management of patients with chronic lymphocytic leukemia with a high risk of adverse outcome: the Mayo Clinic approach.Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia.Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization Genomic variation by whole-genome SNP mapping arrays predicts time-to-event outcome in patients with chronic lymphocytic leukemia: a comparison of CLL and HapMap genotypes.Genomic approaches to chronic lymphocytic leukemia.Clonal evolution, genomic drivers, and effects of therapy in chronic lymphocytic leukemia Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia Treatment resistance in chronic lymphocytic leukemia: the role of the p53 pathway.RNA-based markers as prognostic factors in chronic lymphocytic leukemia.Exploring the genetic landscape in chronic lymphocytic leukemia using high-resolution technologies.Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?Paradigm shifts in the management of poor-risk chronic lymphocytic leukemia.Clonal evolution in chronic lymphocytic leukemia: impact of subclonality on disease progression.The genomic landscape of chronic lymphocytic leukaemia: biological and clinical implications.SNP Array in Hematopoietic Neoplasms: A Review.Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia.Genomic imbalance defines three prognostic groups for risk stratification of patients with chronic lymphocytic leukemia.Array CGH analysis reveals deletion of chromosome 22q11 in CLL with normal karyotype and no fish alterations.Genomic arrays in chronic lymphocytic leukemia routine clinical practice: are we ready to substitute conventional cytogenetics and fluorescencein situhybridization techniques?

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Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

http://www.wikidata.org/entity/Q36843780

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name

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

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Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

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Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

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Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

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Andrzej Jakubowiak

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Chris Saddler

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Harry Erba

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Kerby Shedden

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Lisa Kujawski

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Mark Kaminski

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Peter Ouillette

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Sami N Malek

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P2860

Genomic aberrations and survival in chronic lymphocytic leukemia

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

Chronic lymphocytic leukemia

The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data.

Clinical staging of chronic lymphocytic leukemia.

Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia.

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukemia (CLL) patients at risk of disease progression.

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