Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice
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A Metabolic Immune Checkpoint: Adenosine in Tumor MicroenvironmentImmunotherapy for cancer in the central nervous system: Current and future directionsPerturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis.Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy.Activation of tolerogenic dendritic cells in the tumor draining lymph nodes by CD8+ T cells engineered to express CD40 ligand.Differential requirement for CD70 and CD80/CD86 in dendritic cell-mediated activation of tumor-tolerized CD8 T cells.CD8+ T-cell responses rapidly select for antigen-negative tumor cells in the prostate.Whole-body irradiation increases the magnitude and persistence of adoptively transferred T cells associated with tumor regression in a mouse model of prostate cancerInflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceThe localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapyCutting edge: delay and reversal of T cell tolerance by intratumoral injection of antigen-loaded dendritic cells in an autochthonous tumor model.Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression.Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization.EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice.Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells.Prostate cancer as a model for tumour immunotherapy.Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model.Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic modelProstate cancer immunotherapy.An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia CellsIn vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironmentPersistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independentPaucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.Cell-intrinsic abrogation of TGF-β signaling delays but does not prevent dysfunction of self/tumor-specific CD8 T cells in a murine model of autochthonous prostate cancerTargeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer.Role of dendritic cells in the regulation of antitumor immunityOvercoming obstacles to the effective immunotherapy of human cancer.Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunizationProgress and challenges in the vaccine-based treatment of head and neck cancers.High-avidity autoreactive CD4+ T cells induce host CTL, overcome T(regs) and mediate tumor destruction.Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.The adenosinergic immunomodulatory drugs.Immunotherapy for prostate cancer: an emerging treatment modality.Prostate cancer, tumor immunity and a renewed sense of optimism in immunotherapy.Nonblocking Monoclonal Antibody Targeting Soluble MIC Revamps Endogenous Innate and Adaptive Antitumor Responses and Eliminates Primary and Metastatic Tumors.A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing.Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3B-cell-derived lymphotoxin promotes castration-resistant prostate cancer.Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticlesT cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-β1 cytokine.
P2860
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P2860
Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Rapid tolerization of virus-ac ...... prostate tumors of TRAMP mice
@en
type
label
Rapid tolerization of virus-ac ...... prostate tumors of TRAMP mice
@en
prefLabel
Rapid tolerization of virus-ac ...... prostate tumors of TRAMP mice
@en
P2093
P2860
P356
P1476
Rapid tolerization of virus-ac ...... prostate tumors of TRAMP mice
@en
P2093
Eileen Higham
Herman N Eisen
Jianzhu Chen
K Dane Wittrup
P2860
P304
13003-13008
P356
10.1073/PNAS.0805599105
P407
P577
2008-08-22T00:00:00Z