Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
about
ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling.Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity.The Active Form of Vitamin D Transcriptionally Represses Smad7 Signaling and Activates Extracellular Signal-regulated Kinase (ERK) to Inhibit the Differentiation of a Inflammatory T Helper Cell Subset and Suppress Experimental Autoimmune EncephalomyExchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppressionEpstein-Barr Virus encoded LMP1 regulates cyclin D1 promoter activity by nuclear EGFR and STAT3 in CNE1 cells.Comparative study of expression of smad3 in oral lichen planus and normal oral mucosa.Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice.Targeted Disruption of the JAK2/STAT3 Pathway in Combination with Systemic Administration of Paclitaxel Inhibits the Priming of Ovarian Cancer Stem Cells Leading to a Reduced Tumor Burden.Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Modulation of STAT3-CCL2 Signaling.SiRNA-mediated silencing of Snail-1 induces apoptosis and alters micro RNA expression in human urinary bladder cancer cell line.STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence.Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity.Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.STAT3 selectively interacts with Smad3 to antagonize TGF-βTGF-β and IL-6 family signalling crosstalk: an integrated model.Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-β signaling.Potential Molecular Targets in the Treatment of Lung Cancer Using siRNA Technology.Smad3-STAT3 crosstalk in pathophysiological contexts.siRNA-Mediated Silencing of HMGA2 Induces Apoptosis and Cell Cycle Arrest in Human Colorectal Carcinoma.TGF-β1 expression in regulatory NK1.1-CD4+NKG2D+ T cells dependents on the PI3K-p85α/JNK, NF-κB and STAT3 pathways.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Effects of general anesthesia with or without epidural block on tumor metastasis and mechanisms.
P2860
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P2860
Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Targeting Stat3 and Smad7 to r ...... mor cells in vitro and in vivo
@en
type
label
Targeting Stat3 and Smad7 to r ...... mor cells in vitro and in vivo
@en
prefLabel
Targeting Stat3 and Smad7 to r ...... mor cells in vitro and in vivo
@en
P2093
P2860
P356
P1433
P1476
Targeting Stat3 and Smad7 to r ...... mor cells in vitro and in vivo
@en
P2093
B Baradaran
C M Hovens
L E Taylor
P2860
P2888
P304
P356
10.1038/ONC.2012.260
P407
P577
2012-07-02T00:00:00Z
P5875
P6179
1023324504