Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.
about
The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domainShc and Enigma are both required for mitogenic signaling by Ret/ptc2.Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase AOncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2BRET/PTC and CK19 expression in papillary thyroid carcinoma and its clinicopathologic correlationInfluence of RET/PTC1 and RET/PTC3 oncoproteins in radiation-induced papillary thyroid carcinomas on amounts of cytoskeletal protein species.Advances in cancer cytogenetics.A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells.Case-control genome-wide association study of attention-deficit/hyperactivity disorder.How familial cancer genes and environmentally induced oncogenes have changed the endocrine landscape.H4(D10S170), a gene frequently rearranged with RET in papillary thyroid carcinomas: functional characterization.Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis.Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity.BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancerKinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels.Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage.Low VHL mRNA expression is associated with more aggressive tumor features of papillary thyroid carcinoma.Chromosomal rearrangements in post-Chernobyl papillary thyroid carcinomas: evaluation by spectral karyotyping and automated interphase FISH'Chromosomal Rainbows' Detect Oncogenic Rearrangements of Signaling Molecules in Thyroid Tumors.Detection of RET proto-oncogene point mutations in paraffin-embedded pheochromocytoma specimens by nonradioactive single-strand conformation polymorphism analysis and direct sequencing.Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours.Intracellular signal transduction and modification of the tumor microenvironment induced by RET/PTCs in papillary thyroid carcinoma.RET activation in adult and childhood papillary thyroid carcinoma using a reverse transcriptase-n-polymerase chain reaction approach on archival-nested material.New treatment in advanced thyroid cancer.20 years of RET/PTC in thyroid cancer: clinico-pathological correlations.DNA probe pooling for rapid delineation of chromosomal breakpointsTranslocations in epithelial cancers.A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival.Vandetanib for the treatment of metastatic medullary thyroid cancerTranslational research in endocrine surgery.Molecular cytogenetic characterization of chromosome 9-derived material in a human thyroid cancer cell line.The emerging complexity of gene fusions in cancer.Oncogenes and anti-oncogenes in human epithelial thyroid tumors.Diagnostic and prognostic markers in differentiated thyroid cancer.Accumulation of allelic losses on chromosome 10 in human gliomas at recurrence.Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.The RET proto-oncogene: a challenge to our understanding of disease pathogenesis.Rethinking the role of oncogenes in papillary thyroid cancer initiation.Detection of RET oncogene activation in human papillary thyroid carcinomas by in situ hybridisation.
P2860
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P2860
Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Characterization of an inversi ...... he oncogenic sequence RET/PTC.
@en
type
label
Characterization of an inversi ...... he oncogenic sequence RET/PTC.
@en
prefLabel
Characterization of an inversi ...... he oncogenic sequence RET/PTC.
@en
P2093
P2860
P356
P1476
Characterization of an inversi ...... he oncogenic sequence RET/PTC.
@en
P2093
Bongarzone I
Herrmann MA
Jenkins RB
Pierotti MA
P2860
P304
P356
10.1073/PNAS.89.5.1616
P407
P577
1992-03-01T00:00:00Z