Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
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Cell biology. Metabolic control of cell deathReduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in miceAge-related proteostasis and metabolic alterations in Caspase-2-deficient miceMetabolomic and Gene Expression Profiles Exhibit Modular Genetic and Dietary Structure Linking Metabolic Syndrome Phenotypes in DrosophilaVitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.Sex-specific alterations in glucose homeostasis and metabolic parameters during ageing of caspase-2-deficient miceLipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.Caspase-2: the reinvented enzyme.Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humansCaspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity.Fat, sex and caspase-2.A role for caspase-2 in sphingosine kinase 1 proteolysis in response to doxorubicin in breast cancer cells - implications for the CHK1-suppressed pathway.High-throughput metabolomics approach reveals new mechanistic insights for drug response of phenotypes of geniposide towards alcohol-induced liver injury by using liquid chromatography coupled to high resolution mass spectrometry.Caspases in metabolic disease and their therapeutic potential.To die or not to die: death signaling in nonalcoholic fatty liver disease.Apoptosis and non-alcoholic fatty liver diseases.
P2860
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P2860
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
@en
type
label
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
@en
prefLabel
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
@en
P2093
P2860
P356
P1476
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis
@en
P2093
Alexander Robeson
Christopher B Newgard
Erika Segear Johnson
Joshua L Andersen
Kelly R Lindblom
Olga R Ilkayeva
Robert D Stevens
Sally Kornbluth
P2860
P304
14463-14475
P356
10.1074/JBC.M112.437210
P407
P577
2013-04-03T00:00:00Z