TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice. - Wikidata - wikimedia - TriplyDB

TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.

TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.

http://www.wikidata.org/entity/Q36851875

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Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification Microglial activation by Citrobacter koseri is mediated by TLR4- and MyD88-dependent pathways.Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestins Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke.Current knowledge and future directions of TLR and NOD signaling in sepsis 5-Lipoxygenase activating protein (FLAP) dependent leukotriene biosynthesis inhibition (MK591) attenuates Lipid A endotoxin-induced inflammation.Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis.The Role of TLR2 in Infection and Immunity Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.Bacterial Stimulation of Toll-Like Receptor 4 Drives Macrophages To Hemophagocytose.Suppression of TLR signaling by targeting TIR domain-containing proteins Regulatory actions of Toll-like receptor 2 (TLR2) and TLR4 in Leishmania donovani infection in the liver.Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.Major histocompatibility complex haplotype determines hsp70-dependent protection against measles virus neurovirulence A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.Regulation of innate immune function in bovine oviduct epithelial cells in culture: the homeostatic role of epithelial cells in balancing Th1/Th2 response.Toll-like receptor modulators: a patent review (2006-2010).Modulation of γδ T cell responses by TLR ligands.Innate immune sensors and gastrointestinal bacterial infections.The immune response to severe bacterial infections: consequences for therapy.Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.Inhibition of Toll-Like Receptor Signaling as a Promising Therapy for Inflammatory Diseases: A Journey from Molecular to Nano Therapeutics.Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli.Toll-like receptors: promising therapeutic targets for inflammatory diseases.Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors.Measles virus neurovirulence and host immunity.Toll-like receptor genetic variations in bone marrow transplantation.A novel role for myeloid cell-specific neuropilin 1 in mitigating sepsis.Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis.Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice.Molecular profiling of sepsis in mice using Fourier Transform Infrared Microspectroscopy.Differential induction of inflammatory cytokines and reactive oxygen species in murine peritoneal macrophages and resident fresh bone marrow cells by acute staphylococcus aureus infection: contribution of toll-like receptor 2 (TLR2).Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure.TLR2 and TLR4 mediate the TNFα response to Vibrio vulnificus biotype 1.Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar typhimurium infection, but not for the initiation of bacterial clearance.

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P2860

TLR4-induced IFN-gamma production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.

http://www.wikidata.org/entity/Q36851875

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

TLR4-induced IFN-gamma product ...... Gram-negative sepsis in mice.

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type

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TLR4-induced IFN-gamma product ...... Gram-negative sepsis in mice.

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TLR4-induced IFN-gamma product ...... Gram-negative sepsis in mice.

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TLR4-induced IFN-gamma product ...... Gram-negative sepsis in mice.

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Bruno Daubeuf

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Carsten J Kirschning

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Greg Elson

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Hermann Wagner

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Marina Freudenberg

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Ruth Ferstl

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Stefan Dreher

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Stephan Spiller

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Thomas Mueller

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P2860

Toll-like receptor signalling

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Points of control in inflammation

The immunopathogenesis of sepsis

Interferon gamma receptor deficient mice are resistant to endotoxic shock.

Innate immune sensing and its roots: the story of endotoxin.

Proposed mechanisms and preventative options of Jarisch-Herxheimer reactions.

Early and innovative interventions for severe sepsis and septic shock: taking advantage of a window of opportunity.

Apoptosis and caspases regulate death and inflammation in sepsis.

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10.1084/JEM.20071990

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8

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205

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51418900

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18644971

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Toll-like receptor

Gram-negative bacteria

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2525587

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