Properties of the simian virus 40 (SV40) large T antigens encoded by SV40 mutants with deletions in gene A.
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DNA helicase activity of SV40 large tumor antigenTransactivation of a ribosomal gene by simian virus 40 large-T antigen requires at least three activities of the protein.Role of single-stranded DNA binding activity of T antigen in simian virus 40 DNA replicationSimian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template.Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens.SV40 DNA replication: from the A gene to a nanomachine.Common and unique features of T antigens encoded by the polyomavirus groupAnalysis of a large-T-antigen variant expressed in simian virus 40-transformed mouse cell line mKS-A.Identification of a novel antiapoptotic functional domain in simian virus 40 large T antigen.trans-Dominant and non-trans-dominant mutant simian virus 40 large T antigens show distinct responses to ATP.Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigenAssociation of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutationsMapping the transcriptional transactivation function of simian virus 40 large T antigenTransformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen.Mechanisms of interference with simian virus 40 (SV40) DNA replication by trans-dominant mutants of SV40 large T antigen.Helicase, DNA-binding, and immunological properties of replication-defective simian virus 40 mutant T antigens.The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigenActivation of ATPase activity of simian virus 40 large T antigen by the covalent affinity analog of ATP, fluorosulfonylbenzoyl 5'-adenosineSpecific mutation of a regulatory site within the ATP-binding region of simian virus 40 large T antigenThe T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence.Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant negative phenotype for DNA replicationMapping of helicase and helicase substrate-binding domains on simian virus 40 large T antigen.The growth of simian virus 40 (SV40) host range/adenovirus helper function mutants in an African green monkey cell line that constitutively expresses the SV40 agnoprotein.Simian virus 40 DNA replication correlates with expression of a particular subclass of T antigen in a human glial cell lineThe ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53.Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replicationLinker insertion mutants of simian virus 40 large T antigen that show trans-dominant interference with wild-type large T antigen map to multiple sites within the T-antigen gene.Simian virus 40 host range/helper function mutations cause multiple defects in viral late gene expression.Construction and characterization of hybrid polyomavirus genomes.T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication.Absence of a structural basis for intracellular recognition and differential localization of nuclear and plasma membrane-associated forms of simian virus 40 large tumor antigen.Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.Viral proteins containing the purine NTP-binding sequence pattern.Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity.Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation.Simian virus 40 large T antigen host range domain functions in virion assembly.Monoclonal antibodies as probes for a function of large T antigen during the elongation process of simian virus 40 DNA replication.
P2860
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P2860
Properties of the simian virus 40 (SV40) large T antigens encoded by SV40 mutants with deletions in gene A.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Properties of the simian virus ...... ants with deletions in gene A.
@en
type
label
Properties of the simian virus ...... ants with deletions in gene A.
@en
prefLabel
Properties of the simian virus ...... ants with deletions in gene A.
@en
P2093
P2860
P1433
P1476
Properties of the simian virus ...... ants with deletions in gene A.
@en
P2093
P2860
P304
P407
P577
1986-02-01T00:00:00Z