Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
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Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surfaceColesevelam hydrochloride: evidence for its use in the treatment of hypercholesterolemia and type 2 diabetes mellitus with insights into mechanism of actionSynthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemiaFomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibeSitosterolemia: diagnosis, investigation, and management.Cholesterol and benign prostate disease.Ezetimibe + simvastatin versus doubling the dose of simvastatin in high cardiovascular risk diabetics: a multicenter, randomized trial (the LEAD study)NPC1L1 and cholesterol transportTargets for current pharmacologic therapy in cholesterol gallstone disease.Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes.Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells.Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.Phytosterols and phytosterolemia: gene-diet interactionsMolecular characterization of the NPC1L1 variants identified from cholesterol low absorbersSREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin.The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice.Protein mediators of sterol transport across intestinal brush border membrane.Therapy of gallstone disease: What it was, what it is, what it will beThe association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China.First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.Physiological role of hepatic NPC1L1 in human cholesterol and lipoprotein metabolism: new perspectives and open questions.Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammationLongxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet-Induced ApoE-/- MiceThe role of Niemann-Pick C1 - Like 1 (NPC1L1) in intestinal sterol absorptionInfluence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption.Transporters as drug targets: discovery and development of NPC1L1 inhibitors.Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.The ezetimibe controversy: implications for clinical practice.Ezetimibe plus simvastatin for the treatment of hypercholesterolemia.The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia.Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells.Ezetimibe is an inhibitor of tumor angiogenesis.Nonlinear absorption kinetics of self-emulsifying drug delivery systems (SEDDS) containing tocotrienols as lipophilic molecules: in vivo and in vitro studies.Efficacy and safety of ezetimibe for Japanese patients with dyslipidaemia: The ESSENTIAL Study.[Etiology and pathophysiology of benign prostate hyperplasia].Effect of ezetimibe plus pravastatin on endothelial dysfunction in patients with systemic lupus erythematosus.Effects of ezetimibe on endothelial progenitor cells and microparticles in high-risk patients.Metabolomic strategies to identify tissue-specific effects of cardiovascular drugsPathophysiology of Diabetic Dyslipidemia
P2860
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P2860
Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Zetia: inhibition of Niemann-P ...... tion and treat hyperlipidemia.
@en
type
label
Zetia: inhibition of Niemann-P ...... tion and treat hyperlipidemia.
@en
prefLabel
Zetia: inhibition of Niemann-P ...... tion and treat hyperlipidemia.
@en
P356
P1476
Zetia: inhibition of Niemann-P ...... tion and treat hyperlipidemia.
@en
P2093
Enrico P Veltri
Harry R Davis
P304
P356
10.5551/JAT.14.99
P577
2007-06-01T00:00:00Z