MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
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MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cellsFunctional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Mucins in neoplasms of pancreas, ampulla of Vater and biliary systemPathogenesis of ovarian cancer: clues from selected overexpressed genes.TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer.MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progeniesMechanistic and signaling analysis of Muc4-ErbB2 signaling module: new insights into the mechanism of ligand-independent ErbB2 activity.Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapiesMonoclonal antibodies recognizing the non-tandem repeat regions of the human mucin MUC4 in pancreatic cancer.Aberrant upregulation of MUC4 mucin expression in cutaneous condyloma acuminatum and squamous cell carcinoma suggests a potential role in the diagnosis and therapy of skin diseases.Targeting the EGFR signaling pathway in cancer therapy.Altered Mucins (MUC) trafficking in benign and malignant conditions.MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway.MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells.MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells.MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cellsThe immunomodulating roles of glycoproteins in epithelial ovarian cancer.Immunity and immune suppression in human ovarian cancer.Novel monoclonal antibodies against the proximal (carboxy-terminal) portions of MUC16.Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancerGenetically engineered mucin mouse models for inflammation and cancer.Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapiesNicotine/cigarette smoke promotes metastasis of pancreatic cancer through α7nAChR-mediated MUC4 upregulation.MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1.Ovarian cancer: emerging concept on cancer stem cells.The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer.Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.Emerging role of mucins in epithelial to mesenchymal transition.Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas.Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling.Crk-like adapter protein is required for TGF-β-induced AKT and ERK-signaling pathway in epithelial ovarian carcinomas.Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas.MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-κB signaling in pancreatic cancer.Genomic alterations in mucins across cancersMembrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer.
P2860
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P2860
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
@en
type
label
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
@en
prefLabel
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
@en
P2093
P2860
P356
P1476
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
@en
P2093
M P Ponnusamy
S Chakraborty
P2860
P2888
P304
P356
10.1038/SJ.BJC.6604517
P407
P577
2008-08-01T00:00:00Z
P5875
P6179
1012197511