Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters.
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Use of Cell-Penetrating Peptides in Dendritic Cell-Based VaccinationDexamethasone-(C21-phosphoramide)-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549)Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer CellsProtease-Sensitive Nanomaterials for Cancer Therapeutics and Imaging.Cell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery.Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies.Gemcitabine-(5'-phosphoramidate)-[anti-IGF-1R]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency in populations of pulmonary adenocarcinoma (A549)Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cellsDrug-Bearing Supramolecular Filament Hydrogels as Anti-Inflammatory AgentsCell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.Enhancing cellular uptake of activable cell-penetrating peptide-doxorubicin conjugate by enzymatic cleavage.Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides.Synthesis and Self-Assembly of a Mikto-Arm Star Dual Drug Amphiphile Containing both Paclitaxel and Camptothecin.Multiwalled nanotubes formed by catanionic mixtures of drug amphiphiles.Simultaneous Dual Selective Targeted Delivery of Two Covalent Gemcitabine Immunochemotherapeutics and Complementary Anti-Neoplastic Potency of [Se]-MethylselenocysteineAnti-Neoplastic Cytotoxicity of Gemcitabine-(C4-amide)-[anti-EGFR] in Dual-combination with Epirubicin-(C3-amide)-[anti-HER2/neu] against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3) and the Complementary Effect of Mebendazole.Synthesis and biological evaluation of a peptide-paclitaxel conjugate which targets the integrin αvβ₆Guanidinium-rich, glycerol-derived oligocarbonates: a new class of cell-penetrating molecular transporters that complex, deliver, and release siRNAChemosensitization of doxorubicin in multidrug-resistant cells by unimolecular micelles via increased cellular accumulation and apoptosis.Rendering protein-based particles transiently insoluble for therapeutic applications.Intracellular GSH-activated galactoside photosensitizers for targeted photodynamic therapy and chemotherapy.Fludarabine- (C2-methylhydroxyphosphoramide)- [anti-IGF-1R]: Synthesis and Selectively "Targeted"Anti-Neoplastic Cytotoxicity against Pulmonary Adenocarcinoma (A549)Design of new acid-activated cell-penetrating peptides for tumor drug deliveryAccumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model.Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery.Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System.Reporter nanoparticle that monitors its anticancer efficacy in real time.Cell-penetrating peptides: Possible transduction mechanisms and therapeutic applications.Supramolecular filaments containing a fixed 41% paclitaxel loading.Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.Efflux-mediated antifungal drug resistance.Bioluminescence: a versatile technique for imaging cellular and molecular features.Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applicationsTaxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma.Cell-penetrating peptides: achievements and challenges in application for cancer treatment.Antimicrobial peptides with cell-penetrating peptide properties and vice versa.Recent advances in drug delivery strategies for treatment of ovarian cancer.Nanopreparations for organelle-specific delivery in cancerToward the ideal synthesis and molecular function through synthesis-informed design.
P2860
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P2860
Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Overcoming multidrug resistanc ...... ble octaarginine transporters.
@en
type
label
Overcoming multidrug resistanc ...... ble octaarginine transporters.
@en
prefLabel
Overcoming multidrug resistanc ...... ble octaarginine transporters.
@en
P2093
P2860
P356
P1476
Overcoming multidrug resistanc ...... ble octaarginine transporters.
@en
P2093
Elena A Dubikovskaya
Paul A Wender
Steve H Thorne
Thomas H Pillow
P2860
P304
12128-12133
P356
10.1073/PNAS.0805374105
P407
P577
2008-08-19T00:00:00Z