In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation.
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Type 2 innate lymphoid cells: at the cross-roads in allergic asthmaTCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of DifferentiationThe Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite InfectionSTAT6-dependent and -independent mechanisms in Th2 polarizationThe effects of TLR activation on T-cell development and differentiationNew insights into basophil biology: initiators, regulators, and effectors of type 2 inflammationThe differential expression of IL-4 and IL-13 and its impact on type-2 immunityHistory of interleukin-4Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosisCharacterization of cis-regulatory elements conferring mercury-induced interleukin-4 gene expression in rat mast cells: a role for signal transducer and activator of transcription 6 and TATA box binding sitesDifferentiation of effector CD4 T cell populations (*)T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo.MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasitesPeripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signalingAsthma and allergic inflammation.Filarial infection modulates the immune response to Mycobacterium tuberculosis through expansion of CD4+ IL-4 memory T cells.Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway.Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Memory CD4+ T cells: fate determination, positive feedback and plasticityTranscriptional regulation of Th2 cell differentiation.Basophils are the major producers of IL-4 during primary helminth infection.JAK and STAT signaling molecules in immunoregulation and immune-mediated disease.Helper T-cell identity and evolution of differential transcriptomes and epigenomes.Cytokines of the γ(c) family control CD4+ T cell differentiation and function.Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression.IL-33-activated dendritic cells induce an atypical TH2-type response.IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells.Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responsesRegulation of pathogenesis and immunity in helminth infections.Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses.What determines Th2 differentiation, in vitro and in vivo?Basophils induce Th2 immunity: is this final answer?Transcriptional regulation by STAT6.Evolution of IL4 and pathogen antagonism.CD4+ T helper 2 cells--microbial triggers, differentiation requirements and effector functions.Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins.Cytokine pathways in allergic disease.
P2860
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P2860
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
In vivo studies fail to reveal ...... h2 lymphocyte differentiation.
@en
type
label
In vivo studies fail to reveal ...... h2 lymphocyte differentiation.
@en
prefLabel
In vivo studies fail to reveal ...... h2 lymphocyte differentiation.
@en
P2093
P2860
P356
P1476
In vivo studies fail to reveal ...... h2 lymphocyte differentiation.
@en
P2093
Debbie Scarlett
Graham Le Gros
Jane Hu-Li
Joanna Roberts
Mali Camberis
Melanie Prout
Nicholas van Panhuys
Shiau-Choot Tang
William E Paul
P2860
P304
12423-12428
P356
10.1073/PNAS.0806372105
P407
P577
2008-08-21T00:00:00Z