The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity
about
A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexinMyristoylation-dependent replication and assembly of human immunodeficiency virus 1Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expressionSrc kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate.Identification and characterization of a novel cytoskeleton-associated pp60src substrate.Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinasesStable association of activated pp60src with two tyrosine-phosphorylated cellular proteinspp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-srcTransformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stabilityNonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblastsHeteroatom-substituted fatty acid analogs as substrates for N-myristoyltransferase: an approach for studying both the enzymology and function of protein acylationFunctional analysis of protein N-myristoylation: metabolic labeling studies using three oxygen-substituted analogs of myristic acid and cultured mammalian cells provide evidence for protein-sequence-specific incorporation and analog-specific redistrConformation of a protein kinase C substrate NG(28-43), and its analog in aqueous and sodium dodecyl sulfate micelle solutions.Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.Myristoylation and membrane binding regulate c-Src stability and kinase activityAcetylcholine receptor-associated 43K protein contains covalently bound myristate.Altered membrane association of p60v-src and a murine 63-kDa N-myristoyl protein after incorporation of an oxygen-substituted analog of myristic acidThe disease-resistance gene Pto and the fenthion-sensitivity gene fen encode closely related functional protein kinasesCapsid protein VP4 of poliovirus is N-myristoylated.Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells.The src protein contains multiple domains for specific attachment to membranes.Structure and expression of STK, a src-related gene in the simple metazoan Hydra attenuataThe membrane-binding domain of the Rous sarcoma virus Gag proteinCysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae.Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase.Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicleAssociation of p60c-src with endosomal membranes in mammalian fibroblastsMyristylation of Pr60gag of the murine AIDS-defective virus is required to induce disease and notably for the expansion of its target cellsCD45 tyrosine phosphatase activity and membrane anchoring are required for T-cell antigen receptor signaling.Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis.A myristylated form of the sea oncoprotein can transform chicken embryo fibroblastsSuppression of retroviral MA deletions by the amino-terminal membrane-binding domain of p60src.A major myristylated substrate of protein kinase C and protein kinase C itself are differentially regulated during murine B- and T-lymphocyte development and activation.The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus.The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant.Characterization of the gag/fusion protein encoded by the defective Duplan retrovirus inducing murine acquired immunodeficiency syndromePreassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane.
P2860
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P2860
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
The absence of myristic acid d ...... rosine protein kinase activity
@en
type
label
The absence of myristic acid d ...... rosine protein kinase activity
@en
prefLabel
The absence of myristic acid d ...... rosine protein kinase activity
@en
P2093
P2860
P1433
P1476
The absence of myristic acid d ...... rosine protein kinase activity
@en
P2093
P2860
P304
P407
P577
1986-05-01T00:00:00Z