Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. - Wikidata - wikimedia - TriplyDB

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.

http://www.wikidata.org/entity/Q36867557

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An Evolutionary Perspective of Nutrition and Inflammation as Mechanisms of Cardiovascular Disease The role of oxidative stress and autophagy in atherosclerosis Redox regulation of endothelial cell fate The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside.Differential effect of amylin on endothelial-dependent vasodilation in mesenteric arteries from control and insulin resistant rats Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.Role of interferon alpha in endothelial dysfunction: insights into endothelial nitric oxide synthase-related mechanisms Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart.Impaired compensation to femoral artery ligation in diet-induced obese mice is primarily mediated via suppression of collateral growth by Nox2 and p47phox.Changing the way we think about endothelial cell insulin sensitivity, nitric oxide, and the pathophysiology of type 2 diabetes: the FoxO is loose.Opportunity "nox": a novel approach to preventing endothelial dysfunction in the context of insulin resistance.Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue.New insights into insulin action and resistance in the vasculature.Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet.Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction The Pathophysiological Role of NOX2 in Hypertension and Organ Damage.Microvascular NADPH oxidase in health and disease.Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 Regulates LPS-Induced Inflammation and Alveolar Remodeling in the Developing Lung.Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function.Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice.Crucial roles of Nox2-derived oxidative stress in deteriorating the function of insulin receptors and endothelium in dietary obesity of middle-aged mice.The Contribution of Singlet Oxygen to Insulin Resistance.Evidence stacks up that endothelial insulin resistance is a culprit in atherosclerosis.Comment on: Sukumar et al. Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes 2013;62:2130-2134.Response to Comment on: Sukumar et al. Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes 2013;62:2130-2134.Comment on: Tessari et al. Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo. Diabetes 2013;62:2699-2708.The NOX2-derived reactive oxygen species damaged endothelial nitric oxide system via suppressed BKCa/SKCa in preeclampsia.Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways.Protective effect of sRAGE on fetal development in pregnant rats with gestational diabetes mellitus.Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.Endothelial Cell Metabolism.Letter by Rask-Madsen et al Regarding Article, "Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop".Effects of folic acid on renal endothelial function in patients with diabetic nephropathy: results from a randomized trial.AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway.Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice.Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice

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P2860

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.

http://www.wikidata.org/entity/Q36867557

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Nox2 NADPH oxidase has a criti ...... endothelial cell dysfunction.

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Anna Skromna

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Celio X Santos

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Helen Imrie

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Jessica Smith

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Matthew Gage

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Parkavi Kandavelu

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Piruthivi Sukumar

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Stacey Galloway

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V Kate Gatenby

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P2860

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

Mechanisms linking obesity to insulin resistance and type 2 diabetes

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis.

Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited.

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.

Vascular NADPH oxidases as drug targets for novel antioxidant strategies.

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

Effect of endothelium-specific insulin resistance on endothelial function in vivo.

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