Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation - Wikidata - wikimedia - TriplyDB

Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation

Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation

http://www.wikidata.org/entity/Q36870663

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Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?Connexin hemichannel and pannexin channel electrophysiology: how do they differ?Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions Distinct permeation profiles of the connexin 30 and 43 hemichannels Differentiating connexin hemichannels and pannexin channels in cellular ATP release.Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex.Opening of pannexin- and connexin-based channels increases the excitability of nodose ganglion sensory neurons.Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function.Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes.Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition.Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection Isoform-specific phosphorylation-dependent regulation of connexin hemichannels Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles.Antibodies targeting extracellular domain of connexins for studies of hemichannels Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system?Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.Connexin channel modulators and their mechanisms of action.Extracellular domains play different roles in gap junction formation and docking compatibility.Hunting for connexin hemichannels.Hemichannels: new roles in astroglial function Cx43-hemichannel function and regulation in physiology and pathophysiology: insights from the bovine corneal endothelial cell system and beyond.Cell communication across gap junctions: a historical perspective and current developments.Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer's disease.Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics.Connexin Hemichannels: Methods for Dye Uptake and Leakage.UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes.Connexin channel and its role in diabetic retinopathy.Connexin Channels at the Glio-Vascular Interface: Gatekeepers of the Brain.General anesthetics have differential inhibitory effects on gap junction channels and hemichannels in astrocytes and neurons.Breakthrough Cancer Pain Is Associated with Spinal Gap Junction Activation via Regulation of Connexin 43 in a Mouse Model.Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.Possible role of hemichannels in cancer.Blocking connexin channels improves embryo development of vitrified bovine blastocysts.Connexin hemichannels influence genetically determined inflammatory and hyperproliferative skin diseases.Astrocytes inhibit nitric oxide-dependent Ca(2+) dynamics in activated microglia: involvement of ATP released via pannexin 1 channels.The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs.Connexin 43 and ATP-sensitive potassium channels crosstalk: a missing link in hypoxia/ischemia stress.

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P2860

Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation

http://www.wikidata.org/entity/Q36870663

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2012 nî lūn-bûn

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2012年论文

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name

Connexin mimetic peptides inhi ...... d intracellular Ca2+ elevation

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type

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Connexin mimetic peptides inhi ...... d intracellular Ca2+ elevation

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Connexin mimetic peptides inhi ...... d intracellular Ca2+ elevation

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S00395-012-0304-2

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Basic Research in Cardiology

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Connexin mimetic peptides inhi ...... d intracellular Ca2+ elevation

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Ashish K Gadicherla

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Elke Decrock

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Feliksas F Bukauskas

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Gudrun Antoons

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Karin R Sipido

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Mélissa Bol

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Nan Wang

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William Howard Evans

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P2860

Effects of connexin-mimetic peptides on gap junction functionality and connexin expression in cultured vascular cells

Proliferation of neonatal cardiomyocytes by connexin43 knockdown via synergistic inactivation of p38 MAPK and increased expression of FGF1

Gating and regulation of connexin 43 (Cx43) hemichannels.

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear

Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity.

Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo.

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture.

pH-dependent modulation of voltage gating in connexin45 homotypic and connexin45/connexin43 heterotypic gap junctions

Multichannel recordings from membranes which contain gap junctions. II. Substates and conductance shifts.

Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells.

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s00395-012-0304-2

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10.1007/S00395-012-0304-2

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6

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107

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Marijke De Bock

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2012-10-21T00:00:00Z

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232699252

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23095853

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3662472

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