Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis.
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Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesisThe archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm productionSugar-coated sperm: Unraveling the functions of the mammalian sperm glycocalyxGolgi -mannosidase II cleaves two sugars sequentially in the same catalytic siteB cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esteraseInsect cells encode a class II alpha-mannosidase with unique propertiesThe absence of core fucose up-regulates GnT-III and Wnt target genes: a possible mechanism for an adaptive response in terms of glycan functionRespiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturationMice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency.Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-IIEssential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in miceCystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.Unusual N-glycan structures in alpha-mannosidase II/IIx double null embryos identified by a systematic glycomics approach based on two-dimensional LC mapping and matrix-dependent selective fragmentation method in MALDI-TOF/TOF mass spectrometry.Overexpression of the Golgi-localized enzyme alpha-mannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway.Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol.A deletion in the golgi alpha-mannosidase II gene of Caenorhabditis elegans results in unexpected non-wild-type N-glycan structuresInsight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometryImpaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis.Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.Protein glycosylation in development and disease.Evolutionary considerations in relating oligosaccharide diversity to biological function.Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans.Genetic remodeling of protein glycosylation in vivo induces autoimmune disease.Functional analysis of mouse kinesin motor Kif3C.Congenital disorders of glycosylation: glycosylation defects in man and biological models for their study.Genetic defects in the human glycome.Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.Development of immunoglobulin A nephropathy- like disease in beta-1,4-galactosyltransferase-I-deficient miceEnhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity.The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearingSwainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines.Immune regulation by the ST6Gal sialyltransferase.Protein N-glycosylation in the baculovirus-insect cell system.Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron.Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesisRole of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis.Endoglycosidase and glycoamidase release of N-linked glycansProcessing of N-linked oligosaccharide depends on its location in the anion exchanger, AE1, membrane glycoprotein.Inhibition of the alpha-mannosidase Man2c1 gene expression enhances adhesion of Jurkat cells.
P2860
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P2860
Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Alpha-mannosidase-II deficienc ...... oligosaccharide biosynthesis.
@en
type
label
Alpha-mannosidase-II deficienc ...... oligosaccharide biosynthesis.
@en
prefLabel
Alpha-mannosidase-II deficienc ...... oligosaccharide biosynthesis.
@en
P2093
P1433
P1476
Alpha-mannosidase-II deficienc ...... n oligosaccharide biosynthesis
@en
P2093
K Panneerselvam
K W Moremen
M N Fukuda
P304
P356
10.1016/S0092-8674(00)80322-0
P407
P577
1997-07-01T00:00:00Z