Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
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Modeling congenital disease and inborn errors of development in Drosophila melanogasterFlyBase portals to human disease research using Drosophila modelsDopamine dynamics and signaling in Drosophila: an overview of genes, drugs and behavioral paradigmsImpairment of Drosophila orthologs of the human orphan protein C19orf12 induces bang sensitivity and neurodegenerationThe Cdc48-Vms1 complex maintains 26S proteasome architecture.Drosophila as an In Vivo Model for Human Neurodegenerative DiseaseA drosophila genetic resource of mutants to study mechanisms underlying human genetic diseasesThe intricate relationship between microtubules and their associated motor proteins during axon growth and maintenance.Oxidative-stress induced increase in circulating fatty acids does not contribute to phospholipase A2-dependent appetitive long-term memory failure in the pond snail Lymnaea stagnalis.Taking Stock of the Drosophila Research EcosystemCommunication breakdown: the impact of ageing on synapse structure.Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseasesUsing membrane-targeted green fluorescent protein to monitor neurotoxic protein-dependent degeneration of Drosophila eyesDecoding the ubiquitin-mediated pathway of arthropod disease vectors.DnaJ-1 and karyopherin α3 suppress degeneration in a new Drosophila model of Spinocerebellar Ataxia Type 6.PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila.Gut-neuron interaction via Hh signaling regulates intestinal progenitor cell differentiation in DrosophilaUncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative diseaseDrosophila and experimental neurology in the post-genomic era.Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110Identification of novel modifiers of Aβ toxicity by transcriptomic analysis in the fruitfly.Mutations in palmitoyl-protein thioesterase 1 alter exocytosis and endocytosis at synapses in Drosophila larvae.Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits.Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular DiseasesStress proteins in aging and life span.Fruitful research: drug target discovery for neurodegenerative diseases in Drosophila.A mitocentric view of Parkinson's disease.Chromatin regulators in neurodevelopment and disease: Analysis of fly neural circuits provides insights: Networks of chromatin regulators and transcription factors underlie Drosophila neurogenesis and cognitive defects in intellectual disability andMorgan's legacy: fruit flies and the functional annotation of conserved genes.Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2.An automated image analysis method to measure regularity in biological patterns: a case study in a Drosophila neurodegenerative model.Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking.Autophagy in Drosophila: from historical studies to current knowledgeThe Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D.Stress-induced Cdk5 activity enhances cytoprotective basal autophagy in Drosophila melanogaster by phosphorylating acinus at serine437.Overexpression of Drosophila frataxin triggers cell death in an iron-dependent manner.Mass Histology to Quantify Neurodegeneration in Drosophila.Drosophila melanogaster White Mutant w1118 Undergo Retinal Degeneration.A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo.
P2860
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P2860
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
@en
type
label
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
@en
prefLabel
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
@en
P2860
P50
P1476
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
@en
P2093
P2860
P304
P356
10.1146/ANNUREV-GENET-110711-155456
P577
2012-09-04T00:00:00Z