MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.
about
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADDMembrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cellsMucins in cancer: function, prognosis and therapyCHD7 expression predicts survival outcomes in patients with resected pancreatic cancer.Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α.Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell linePrognostic significance of mucin expression in urothelial bladder cancer.MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.miR-1226 targets expression of the mucin 1 oncoprotein and induces cell death.MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expressionMucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathwaysPrevention of lung injury by Muc1 mucin in a mouse model of repetitive Pseudomonas aeruginosa infection.Molecular targeted approaches for treatment of pancreatic cancer.NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells.MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.Monoclonal antibodies in the treatment of pancreatic cancer.MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor.Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axisUpdate on Mucin-1 immunotherapy in cancer: a clinical perspective.MUC1 extracellular domain confers resistance of epithelial cancer cells to anoikis.MUC1-C Oncoprotein Integrates a Program of EMT, Epigenetic Reprogramming and Immune Evasion in Human Carcinomas.ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF.The Tat-conjugated N-terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1-expressing tumours.DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.MUC1-C promotes the suppressive immune microenvironment in non-small cell lung cancer.MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells.Decreased expression of MUC1 induces apoptosis and inhibits migration in pancreatic cancer PANC-1 cells via regulation of Slug pathway.SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line.MUC1-C Induces PD-L1 and Immune Evasion in Triple-Negative Breast Cancer.Paradox CA 15-3 increase in metastatic breast cancer patients treated with everolimus: a change of paradigm in a case series.CA 15-3 serum levels in patients with ductal breast carcinoma: relationship with clinicopathological parameters and tumor markers.
P2860
Q24316876-1817ACFD-6BBA-46AF-A660-03DAFF85F62EQ24601584-96FF5B29-83C6-453B-AFB1-20D8542CA0B2Q24633765-38B9EDCB-F150-404E-A76E-213D266F24B6Q33630872-30EA81F5-4AD2-443C-9A96-9A24152ED85EQ33651423-FADCFE47-84C6-4595-8F20-D94E42FB3395Q34071695-AC2E45CC-1289-428E-8B61-C4F329CE26E3Q34121441-10B503F6-D571-48D7-B90B-ECDB9CA10711Q34389169-70807E74-2773-4162-A9C1-45C3613BF0E5Q34522311-4076DDB2-909B-4077-8267-3CE5959FAF9EQ34524741-8CE92D32-6DF0-4023-AC5E-220D1C433224Q35785117-EE4C0726-542B-4F58-BE79-F1C46A357246Q36164674-D3E7FB2C-8CCB-44A9-A1BA-1C5C8571DEBAQ36174910-99963E09-7ECD-4534-AE1E-9E44AC96C8A6Q36586166-44A4ED13-7217-4E1E-A702-61EA1CA82C57Q36621615-4BA107CD-2972-4434-B3B8-DED11F887088Q36821095-73909CE0-03AA-4721-A11A-6D6FDB1EAC24Q37355568-9EDC1408-F855-46AC-A9C9-093248471C89Q37385169-8D8F4A40-AA9F-408D-955A-421C483B7D08Q37457758-0005CB2F-D6CD-45CA-8FFD-F7300992CA0BQ38603410-BC90A4AA-BE07-4C7D-BBAB-790B7042F144Q38951257-CFE4CCB0-2ABD-4662-AB7B-7AA1245E3EFAQ39182659-FAAE3B71-2895-41C5-BA79-0D4A4CE14A33Q39218236-4B18A212-7F41-4A2A-818A-838B4B6F66B7Q39669238-B25C831F-1A28-402B-8F2E-D0842959BC0DQ39802340-87FD5F5E-5653-40D2-8478-C16FC73DC587Q47291846-CE9DFA9D-C968-4E90-9646-2C2415DEF0E2Q47951334-75A0456B-2B12-4A93-8697-8E5C1CE4DA59Q48146766-7E448582-9D82-401A-B65C-BE159CB7AFD8Q50225593-0AF095F9-0CFF-4A6C-B000-00A13BD7D87CQ50234490-BFDB1C08-4D28-4392-80B4-BE96006C2597Q52742033-848C92BC-09D1-4601-A7ED-76258AC3BD92Q53766709-1E90D6A7-578A-465C-89E6-DC7D2A206E40Q54559227-9672B814-D280-40AB-BC68-876982362C66
P2860
MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
MUC1 oncoprotein blocks death ...... ting recruitment of caspase-8.
@en
type
label
MUC1 oncoprotein blocks death ...... ting recruitment of caspase-8.
@en
prefLabel
MUC1 oncoprotein blocks death ...... ting recruitment of caspase-8.
@en
P2093
P2860
P1433
P1476
MUC1 oncoprotein blocks death ...... ting recruitment of caspase-8.
@en
P2093
Deepak Raina
Donald Kufe
Naoki Agata
Rehan Ahmad
Surender Kharbanda
Takeshi Kawano
P2860
P304
P356
10.1158/0008-5472.CAN-08-0464
P407
P577
2008-08-01T00:00:00Z