Radiosynthesis and evaluation of [11C]EMPA as a potential PET tracer for orexin 2 receptors.

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A potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression.Failed PET Application Attempts in the Past, Can We Avoid Them in the Future?

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Radiosynthesis and evaluation of [11C]EMPA as a potential PET tracer for orexin 2 receptors.

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2013 nî lūn-bûn

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Radiosynthesis and evaluation ...... tracer for orexin 2 receptors.

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Radiosynthesis and evaluation ...... tracer for orexin 2 receptors.

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Radiosynthesis and evaluation ...... tracer for orexin 2 receptors.

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P1476

Radiosynthesis and evaluation ...... tracer for orexin 2 receptors

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Changning Wang

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Christian K Moseley

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Colin M Wilson

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Ramesh Neelamegam

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Stephen M Carlin

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P2860

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists

Promotion of sleep by targeting the orexin system in rats, dogs and humans.

Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists.

Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists.

Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor.

Hypocretin (orexin): role in normal behavior and neuropathology.

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3389-3392

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scholarly article

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10.1016/J.BMCL.2013.03.079

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English

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P478

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Jacob M. Hooker

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2013-04-02T00:00:00Z

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23601709

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3664928

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Radiosynthesis and evaluation of [11C]EMPA as a potential PET tracer for orexin 2 receptors.

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P2860

P2860

Radiosynthesis and evaluation of [11C]EMPA as a potential PET tracer for orexin 2 receptors.

description

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type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932