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Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

http://www.wikidata.org/entity/Q36880000

about

Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5'-O-phosphorothioates to nucleoside 5'-O-phosphates Applications of mass spectrometry to the study of siRNA.Pharmacology, pharmacokinetics, and metabolism of the DNA-decoy AYX1 for the prevention of acute and chronic post-surgical pain Lipid-based systems for the intracellular delivery of genetic drugs.Capillary electrophoresis in clinical and forensic analysis: recent advances and breakthrough to routine applications.Pharmacokinetic applications of capillary electrophoresis.Determination of therapeutic oligonucleotides using capillary gel electrophoresis.DETECTING LOW-LEVEL SYNTHESIS IMPURITIES IN MODIFIED PHOSPHOROTHIOATE OLIGONUCLEOTIDES USING LIQUID CHROMATOGRAPHY - HIGH RESOLUTION MASS SPECTROMETRY.Separation of peptide fragments of a protein kinase C substrate fused to a β-hairpin by capillary electrophoresis Inhibition of TNF-alpha gene expression and bioactivity by site-specific transcription factor-binding oligonucleotides.A Novel and Intuitive Method of Displaying and Interacting with Mass Difference Information: Application to Oligonucleotide Drug Impurities.Iron Oxide Nanoparticles Coated with a Phosphorothioate Oligonucleotide and a Cationic Peptide: Exploring Four Different Ways of Surface Functionalization.The Use of Tricyclo-DNA Oligomers for the Treatment of Genetic Disorders.

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P2860

Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

http://www.wikidata.org/entity/Q36880000

description

1997 nî lūn-bûn

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

@zh-tw

1997年论文

@wuu

1997年论文

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1997年论文

@zh-cn

name

Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

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type

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Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

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Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

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Nucleic Acids Research

P1476

Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids.

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P2093

Belenky A

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Bourque A

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Cohen AS

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Gilar M

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Smisek DL

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P2860

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

A nonradioisotope approach to study the in vivo metabolism of phosphorothioate oligonucleotides.

Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

Bond order and charge localization in nucleoside phosphorothioates.

Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides.

Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.

Antisense oligonucleotides: towards clinical trials.

Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects.

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3615-3620

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scholarly article

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10.1093/NAR/25.18.3615

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18

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25

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9278481

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146928

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