Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer. - Wikidata - wikimedia - TriplyDB

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.

http://www.wikidata.org/entity/Q36881446

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Novel therapeutic targets for pancreatic cancer Cancer of the Pancreas: Molecular Pathways and Current Advancement in Treatment γ-Secretase inhibitors and modulators.Targeting the Notch signaling pathway in cancer therapeutics The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer A NOTCH-sensitive uPAR-regulated oncolytic adenovirus effectively suppresses pancreatic tumor growth and triggers synergistic anticancer effects with gemcitabine and nab-paclitaxel Leptin-Notch signaling axis is involved in pancreatic cancer progression Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases.Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics.Novel strategies for managing pancreatic cancer.New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype New insights into pancreatic cancer stem cells.Xanthohumol inhibits Notch signaling and induces apoptosis in hepatocellular carcinoma New targeted therapies in pancreatic cancer.Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell.The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer.Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.The roles of FOXM1 in pancreatic stem cells and carcinogenesis Pancreatic cancer stroma: understanding biology leads to new therapeutic strategies.Optimum chemotherapy in the management of metastatic pancreatic cancer Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention.Stem cell-directed therapies in pancreatic cancer.Brief overview of selected approaches in targeting pancreatic adenocarcinoma.TTD consensus document on the diagnosis and management of exocrine pancreatic cancer.Molecular pathways: translational and therapeutic implications of the Notch signaling pathway in cancer Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis.Notch-4 silencing inhibits prostate cancer growth and EMT via the NF-κB pathway.Notch Pathway Inhibition Using PF-03084014, a γ-Secretase Inhibitor (GSI), Enhances the Antitumor Effect of Docetaxel in Prostate Cancer.Expression of p53, p16, cyclin D1, epidermal growth factor receptor and Notch1 in patients with temporal bone squamous cell carcinoma.Expression of CD24, a Stem Cell Marker, in Pancreatic and Small Intestinal Neuroendocrine Tumors.Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives.Shifting paradigm of developing biologics for the treatment of pancreatic adenocarcinoma.Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer.Targeting Notch1 inhibits invasion and angiogenesis of human breast cancer cells via inhibition Nuclear Factor-κB signaling.

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P2860

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.

http://www.wikidata.org/entity/Q36881446

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Notch signaling pathway target ...... c spread in pancreatic cancer.

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Notch signaling pathway target ...... ic spread in pancreatic cancer

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Anirban Maitra

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Elizabeth De Oliveira

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Mirte M Streppel

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N V Rajeshkumar

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Nathaniel R Campbell

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Roeland F de Wilde

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Shinichi Yabuuchi

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Shweta G Pai

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Zeshaan A Rasheed

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P2860

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Notch: a key regulator of tumor angiogenesis and metastasis

The pancreas cancer microenvironment

Identification of selective inhibitors of cancer stem cells by high-throughput screening

Identification of pancreatic cancer stem cells

NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

Pancreatic cancer

Notch inhibition as a promising new approach to cancer therapy.

Pancreatic cancer.

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